Targeting the tumor microenvironment: JAK-STAT3 signaling - Test2 - elhamkhani - TriplyDB

Targeting the tumor microenvironment: JAK-STAT3 signaling

Targeting the tumor microenvironment: JAK-STAT3 signaling

http://www.wikidata.org/entity/Q26825658

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Natural Killer Cell-Based Therapies Targeting Cancer: Possible Strategies to Gain and Sustain Anti-Tumor Activity Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis Cancer metastases: challenges and opportunities Astaxanthin inhibits JAK/STAT-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.Cross talk between the TM4SF5/focal adhesion kinase and the interleukin-6/STAT3 pathways promotes immune escape of human liver cancer cells.AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells.Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization Overexpression of sphingosine-1-phosphate receptor 1 and phospho-signal transducer and activator of transcription 3 is associated with poor prognosis in rituximab-treated diffuse large B-cell lymphomas.Dual high expression of STAT3 and cyclinD1 is associated with poor prognosis after curative resection of esophageal squamous cell carcinoma.Cancer-associated fibroblasts promote proliferation of endometrial cancer cells Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch.Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer.Expression of signal transducer and activator of transcription 3 and its phosphorylated form is significantly upregulated in patients with papillary thyroid cancer.Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma.A genetic view of laryngeal cancer heterogeneity The Role of STAT3 in Thyroid Cancer.TM4SF5-Mediated Roles in the Development of Fibrotic Phenotypes Microenvironmental clues for glioma immunotherapy.Rho GTPases modulate malignant transformation of tumor cells.From physiology to disease and targeted therapy: interleukin-6 in inflammation and inflammation-associated carcinogenesis.The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland.Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.Bone marrow microenvironment confers imatinib resistance to chronic myelogenous leukemia and oroxylin A reverses the resistance by suppressing Stat3 pathway.Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops.Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma.Expression analysis of apolipoprotein E and its associated genes in gastric cancer.Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue.Combination curcumin and (-)-epigallocatechin-3-gallate inhibits colorectal carcinoma microenvironment-induced angiogenesis by JAK/STAT3/IL-8 pathway.Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells.Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling.20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells.Investigation on changes of modularity and robustness by edge-removal mutations in signaling networks.Mutations in the signal transducer and activator of transcription family of genes in cancer.Multifaceted Roles of Interleukin-6 in Adipocyte-Breast Cancer Cell Interaction.Targeting the IL-6/JAK/STAT3 signalling axis in cancer.

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P2860

Targeting the tumor microenvironment: JAK-STAT3 signaling

http://www.wikidata.org/entity/Q26825658

description

2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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label

Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Targeting the tumor microenvironment: JAK-STAT3 signaling

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Eirini Bournazou

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Jacqueline Bromberg

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P2860

Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

Regulation of STAT3-mediated signaling by LMW-DSP2

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Somatic STAT3 mutations in large granular lymphocytic leukemia

IL-23 promotes tumour incidence and growth

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice

STATs in cancer inflammation and immunity: a leading role for STAT3

STATs and gene regulation

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e23828

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10.4161/JKST.23828

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2

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24058812

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3710325

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