about
Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditionsSignal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytesA gain-of-function mutation in STAT6Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interactionStat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activationIdentification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approachRequirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium.The MAP Kinase Cascade Is Activated prior to the Induction of Gliosis in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Model of Dopaminergic Neurotoxicity.Early activation of STAT3 regulates reactive astrogliosis induced by diverse forms of neurotoxicityNucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domainThe coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3A transcriptional corepressor of Stat1 with an essential LXXLL signature motifIdentification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activationInositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cellshTid-1, a human DnaJ protein, modulates the interferon signaling pathwayErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerAcetylation directs survivin nuclear localization to repress STAT3 oncogenic activitySTAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasisIdentification of a nuclear Stat1 protein tyrosine phosphataseJAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3Tid1 isoforms are mitochondrial DnaJ-like chaperones with unique carboxyl termini that determine cytosolic fateInhibition of Stat1-mediated gene activation by PIAS1Mutational analysis of the STAT6 SH2 domainRole of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm inductionIdentification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptorThe AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLFDifferential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loopA WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damageIdentification of two RNA-binding proteins associated with human telomerase RNAAntiviral actions of interferonsThe Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factorsDifferential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbetaInteracting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
STATs and gene regulation
@ast
STATs and gene regulation
@en
type
label
STATs and gene regulation
@ast
STATs and gene regulation
@en
prefLabel
STATs and gene regulation
@ast
STATs and gene regulation
@en
P3181
P1433
P1476
STATs and gene regulation
@en
P2093
Darnell JE Jr
P304
P3181
P356
10.1126/SCIENCE.277.5332.1630
P407
P577
1997-09-12T00:00:00Z