eIF5A isoforms and cancer: two brothers for two functions?
about
Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformationInhibition of eIF5A results in aberrant uterine natural killer cell function and embryo loss in mice.eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequencesExpression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapiesCisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2.SNS01-T modulation of eIF5A inhibits B-cell cancer progression and synergizes with bortezomib and lenalidomide.Hypusination of eukaryotic initiation factor 5A via cAMP-PKA-ERK1/2 pathway is required for ligand-induced downregulation of LH receptor mRNA expression in the ovary.Modulation of eIF5A expression using SNS01 nanoparticles inhibits NF-κB activity and tumor growth in murine models of multiple myeloma.The translation factor eIF5A and human cancer.Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation.Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cellsEukaryotic translation initiation factor 5A2 regulates the migration and invasion of hepatocellular carcinoma cells via pathways involving reactive oxygen species.Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea.A supervised network analysis on gene expression profiles of breast tumors predicts a 41-gene prognostic signature of the transcription factor MYB across molecular subtypes.Roles of eukaryotic initiation factor 5A2 in human cancer.eIF5A and EF-P: two unique translation factors are now traveling the same road.Polyamines are oncometabolites that regulate the LIN28/let-7 pathway in colorectal cancer cells.eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth.The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.Functions of Polyamines in MammalsThe spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5A.Prognostic marker microRNA-125b inhibits tumorigenic properties of hepatocellular carcinoma cells via suppressing tumorigenic molecule eIF5A2.Structure, synthesis and biological properties of the pentacyclic guanidinium alkaloids.Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins.From Protein Synthesis to Molecular Biology: The Appealing Tale of eIF-5A.Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment.Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease.
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eIF5A isoforms and cancer: two brothers for two functions?
description
2013 nî lūn-bûn
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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
eIF5A isoforms and cancer: two brothers for two functions?
@ast
eIF5A isoforms and cancer: two brothers for two functions?
@en
eIF5A isoforms and cancer: two brothers for two functions?
@nl
type
label
eIF5A isoforms and cancer: two brothers for two functions?
@ast
eIF5A isoforms and cancer: two brothers for two functions?
@en
eIF5A isoforms and cancer: two brothers for two functions?
@nl
prefLabel
eIF5A isoforms and cancer: two brothers for two functions?
@ast
eIF5A isoforms and cancer: two brothers for two functions?
@en
eIF5A isoforms and cancer: two brothers for two functions?
@nl
P2093
P2860
P3181
P1433
P1476
eIF5A isoforms and cancer: two brothers for two functions?
@en
P2093
P2860
P2888
P304
P3181
P356
10.1007/S00726-011-1182-X
P407
P577
2011-12-03T00:00:00Z
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P6179
1001199243