about
Rrp6: Integrated roles in nuclear RNA metabolism and transcription terminationHuman Mendelian diseases related to abnormalities of the RNA exosome or its cofactorsRNA helicase proteins as chaperones and remodelersAltered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear ExosomeThe human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesisThe exosome complex establishes a barricade to erythroid maturationThe exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathwayEXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia.Links between mRNA splicing, mRNA quality control, and intellectual disabilityTailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi.The SKIV2L RNA exosome limits activation of the RIG-I-like receptorsThe Mtr4 ratchet helix and arch domain both function to promote RNA unwindingAnalysis of RNA decay factor mediated RNA stability contributions on RNA abundance.Noncoding RNA transcription targets AID to divergently transcribed loci in B cells.Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeastThe fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.The exosome controls alternative splicing by mediating the gene expression and assembly of the spliceosome complex.DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts.Exosomal Protein Deficiencies: How Abnormal RNA Metabolism Results in Childhood-Onset Neurological DiseasesA conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.Molecular Mechanism of Processive 3' to 5' RNA Translocation in the Active Subunit of the RNA Exosome Complex.Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II.Attacked from All Sides: RNA Decay in Antiviral Defense.The eukaryotic RNA exosomeExosome substrate targeting: the long and short of it.The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.RNA degradation in antiviral immunity and autoimmunityThe roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.Insight into the RNA Exosome Complex Through Modeling Pontocerebellar Hypoplasia Type 1b Disease Mutations in Yeast.The interplay between transcription and mRNA degradation in Saccharomyces cerevisiaeAltered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy.RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism.Autophagy mediates nonselective RNA degradation in starving yeast.RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities.The RNA exosome and RNA exosome-linked disease.Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.The RNA exosome promotes transcription termination of backtracked RNA polymerase II.Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt.RNA surveillance by the nuclear RNA exosome: mechanisms and significance.
P2860
Q26776427-63DA6188-240F-4971-83FE-FE0F00BB1E6DQ27000489-D755CFC1-61F0-4AA6-8148-874B182653B4Q27025517-8D130A8C-9DFF-4912-A339-D2C04BEEE892Q27930888-417032E4-BC77-4130-8CBB-FE40DA929C7AQ27939455-33337F6E-9C0F-4A38-9A5B-18EC8D99EDA2Q28117297-C4FCF404-B728-4A02-AE79-A24359A23E27Q28245809-476E1EDB-F3D8-4DC1-869F-A159BCF4A708Q28545135-DC6C0961-CF8F-4AA5-B719-AE4D9BB1EE13Q30434640-FBB7B805-B56C-419E-B6B4-070597170627Q33364292-F7E58F48-9467-42B8-9A06-6FB6CDD124ACQ33762828-AA959A3E-496B-4C0C-9785-D9B4D1E3FD4CQ34071054-027DC2E7-25AC-49BB-9439-BC882B154E80Q34711978-2F34D3F4-901C-4B55-B376-BD3AB5F4AB13Q35177862-986CA802-3E7D-4FF0-B60C-374F8DE2C51BQ35213438-4B615A89-916C-4144-B10A-511720B9197BQ35664130-66F31DB4-D9DB-49C1-8B60-BDE47DCA7C30Q35681747-FE1AD41F-F8AA-4A6B-A9F0-061C7F339548Q35996334-5AF1735A-E5F1-433F-B1E7-CABCB6156259Q36199560-8DD4F95F-9C0A-4D0D-B9F9-58F48CCBEEB8Q36838271-6E824210-0119-4EAB-99DD-DBA68A4FE47DQ37151378-CD775A2E-8558-4AD5-83F9-C569D0C14814Q37184211-E60D5699-AA3B-471F-B169-F865C1775289Q37407640-E6DFE45D-9233-44E0-B45E-DCB31270AC0AQ37628197-55FFEBD7-9363-4FE1-9E87-4FCCABF6DD8BQ37700949-03145091-FFC2-498F-BDAB-9A78A206E103Q38238668-1474EA54-9365-43AA-9385-6E6FA134998BQ38303499-C8DEB9E3-24EE-4886-9B3A-C396283C012EQ38364656-23D94D8B-499F-4DD2-B8AA-15C5AF8380D7Q38487234-782474CA-35E4-44EC-8EF5-83E9ABD7A9ACQ38736826-CBC54A78-323B-4A3F-8424-F8787AF53E04Q39434281-BF0DFE69-5C7A-4718-9ABE-4E3C8F024CBFQ39756070-C887A3CD-4B15-4211-93CC-14B4F12B5479Q40709822-FC783F0E-DE62-4B8C-9645-06E5334FA624Q41881632-58658269-D227-4B40-B4BF-DF724D8BB27FQ47279037-EBEBB57E-BAE5-477A-9C16-C00702C363AAQ47593634-1C6977F5-CB4C-41AA-9145-140AF3E3B371Q48259886-0ED07753-F7D0-47A8-97B9-F92C1A131F0DQ48268876-D8B60C59-6A6A-4167-A468-3CEF7A4AE27EQ48929989-637E25BE-5FCC-408A-8711-9CD2C56649EEQ52599402-83699F94-D652-409E-86E2-79FBC201E03B
P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Threading the barrel of the RNA exosome
@ast
Threading the barrel of the RNA exosome
@en
Threading the barrel of the RNA exosome
@nl
type
label
Threading the barrel of the RNA exosome
@ast
Threading the barrel of the RNA exosome
@en
Threading the barrel of the RNA exosome
@nl
prefLabel
Threading the barrel of the RNA exosome
@ast
Threading the barrel of the RNA exosome
@en
Threading the barrel of the RNA exosome
@nl
P2860
P921
P3181
P1476
Threading the barrel of the RNA exosome
@en
P2860
P304
P3181
P356
10.1016/J.TIBS.2013.06.013
P407
P577
2013-10-01T00:00:00Z