Aurora kinase A in gastrointestinal cancers: time to target - Test2 - elhamkhani - TriplyDB

Aurora kinase A in gastrointestinal cancers: time to target

Aurora kinase A in gastrointestinal cancers: time to target

http://www.wikidata.org/entity/Q26864277

about

Emerging molecular classifications and therapeutic implications for gastric cancer Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division Aurora kinases: novel therapy targets in cancers Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.RNA interference in head and neck oncology.Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases.Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas.Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior.Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma.Characterization of ovarian clear cell carcinoma using target drug-based molecular biomarkers: implications for personalized cancer therapy.Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe.Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.Activation of EIF4E by Aurora Kinase A Depicts a Novel Druggable Axis in Everolimus-Resistant Cancer Cells.Predictive biomarkers along gastric cancer pathogenetic pathways.Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets.Network analysis revealed aurora kinase dysregulation in five gynecological types of cancer.CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients.A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.Analysis of potential genes associated with primary cilia in bladder cancer

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P2860

Aurora kinase A in gastrointestinal cancers: time to target

http://www.wikidata.org/entity/Q26864277

description

2015 nî lūn-bûn

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2015 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2015 թվականի մայիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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type

label

Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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prefLabel

Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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Aurora kinase A in gastrointestinal cancers: time to target

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Molecular Cancer

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Aurora kinase A in gastrointestinal cancers: time to target

@en

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Abbes Belkhiri

http://www.w3.org/2001/XMLSchema#string

Ahmed Katsha

http://www.w3.org/2001/XMLSchema#string

Laura Goff

http://www.w3.org/2001/XMLSchema#string

Wael El-Rifai

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Creative Commons Attribution

P2860

Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma

Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73

Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs

Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways

The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells

Cancer statistics, 2013

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

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10.1186/S12943-015-0375-4

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gastrointestinal system cancer

gastrointestinal neoplasm

cell cycle proteins

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