Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
about
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersTargeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancerRho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis.LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosisCentrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinaseThe LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complexAjuba LIM proteins are snail/slug corepressors required for neural crest development in XenopusTumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activationAjuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factorThe decision to enter mitosis: feedback and redundancy in the mitotic entry networkPlk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBoraA cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alphaIntegrin-linked kinase localizes to the centrosome and regulates mitotic spindle organizationElucidation of the function of type 1 human methionine aminopeptidase during cell cycle progressionThe LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migrationNon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionCross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle AssemblyThe Ran Pathway in Drosophila melanogaster MitosisAurora kinase A in gastrointestinal cancers: time to targetCell division: control of the chromosomal passenger complex in time and spaceAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleA Cell Biologist's Field Guide to Aurora Kinase InhibitorsTPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis.Two TPX2-dependent switches control the activity of Aurora ASelective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenThe aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cellsCentrosome - a promising anti-cancer targetPlk1- and beta-TrCP-dependent degradation of Bora controls mitotic progressionBora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entryIdentification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction modelAurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cellsBRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transitionThe focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosomeDirect association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-CPhosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoANEDD9 depletion destabilizes Aurora A kinase and heightens the efficacy of Aurora A inhibitors: implications for treatment of metastatic solid tumors
P2860
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P2860
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
description
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im September 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/09/05)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/09/05)
@nl
наукова стаття, опублікована у вересні 2003
@uk
مقالة علمية (نشرت في 5-9-2003)
@ar
name
Aurora-A and an interacting ac ...... otic commitment in human cells
@ast
Aurora-A and an interacting ac ...... otic commitment in human cells
@en
Aurora-A and an interacting ac ...... otic commitment in human cells
@nl
type
label
Aurora-A and an interacting ac ...... otic commitment in human cells
@ast
Aurora-A and an interacting ac ...... otic commitment in human cells
@en
Aurora-A and an interacting ac ...... otic commitment in human cells
@nl
prefLabel
Aurora-A and an interacting ac ...... otic commitment in human cells
@ast
Aurora-A and an interacting ac ...... otic commitment in human cells
@en
Aurora-A and an interacting ac ...... otic commitment in human cells
@nl
P2093
P3181
P1433
P1476
Aurora-A and an interacting ac ...... otic commitment in human cells
@en
P2093
Dongwei Zhang
Hideyuki Saya
Katsuyoshi Hatakeyama
Masayuki Nitta
Naoko Kunitoku
Takashi Sasayama
Tomotoshi Marumoto
Toru Hirota
P304
P3181
P356
10.1016/S0092-8674(03)00642-1
P407
P577
2003-09-05T00:00:00Z