about
Structural mechanism for the specific assembly and activation of the extracellular signal regulated kinase 5 (ERK5) moduleTargeting MAPK Signaling in Age-Related Macular DegenerationERK5 and Cell Proliferation: Nuclear Localization Is What MattersIn search of the molecular mechanisms mediating the inhibitory effect of the GnRH antagonist degarelix on human prostate cell growthKinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancerThe MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children.Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.Epitope-guided engineering of monobody binders for in vivo inhibition of Erk-2 signaling.MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesisTranscriptome analysis of the white body of the squid Euprymna tasmanica with emphasis on immune and hematopoietic gene discovery.ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells.MEK5-ERK5 pathway associates with poor survival of breast cancer patients after systemic treatments.Phosphorylation of ERK5 on Thr732 is associated with ERK5 nuclear localization and ERK5-dependent transcription.ERK5 activation is essential for osteoclast differentiation.A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.ERK5 negatively regulates tobacco smoke-induced pulmonary epithelial-mesenchymal transition.MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer.The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.Increased IGF-IEc expression and mechano-growth factor production in intestinal muscle of fibrostenotic Crohn's disease and smooth muscle hypertrophy.ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma.EGCG Suppresses ERK5 Activation to Reverse Tobacco Smoke-Triggered Gastric Epithelial-Mesenchymal Transition in BALB/c Mice.Functions of microRNA-143 in the apoptosis, invasion and migration of nasopharyngeal carcinomaErk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes.Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.CD44 standard and CD44v10 isoform expression on leukemia cells distinctly influences niche embedding of hematopoietic stem cellsProtein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance.An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes.Identification of ponatinib and other known kinase inhibitors with potent MEKK2 inhibitory activity.The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug targetMEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism.The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 PathwayUbiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.Protein-protein interaction analysis in crude bacterial lysates using combinational method of 19F site-specific incorporation and 19F NMRAnalysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity.Role of AP-2α and MAPK7 in the regulation of autocrine TGF-β/miR-200b signals to maintain epithelial-mesenchymal transition in cholangiocarcinoma.Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2).
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
MEK5/ERK5 pathway: the first fifteen years
@ast
MEK5/ERK5 pathway: the first fifteen years
@en
MEK5/ERK5 pathway: the first fifteen years
@nl
type
label
MEK5/ERK5 pathway: the first fifteen years
@ast
MEK5/ERK5 pathway: the first fifteen years
@en
MEK5/ERK5 pathway: the first fifteen years
@nl
prefLabel
MEK5/ERK5 pathway: the first fifteen years
@ast
MEK5/ERK5 pathway: the first fifteen years
@en
MEK5/ERK5 pathway: the first fifteen years
@nl
P2093
P2860
P3181
P1476
MEK5/ERK5 pathway: the first fifteen years
@en
P2093
Barbara A. Drew
Barbara S. Beckman
Matthew E. Burow
P2860
P3181
P356
10.1016/J.BBCAN.2011.10.002
P407
P577
2012-01-01T00:00:00Z