Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces
about
Diversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interactionβ-Turn mimetic-based stabilizers of protein-protein interactions for the study of the non-canonical roles of leucyl-tRNA synthetase.Direct comparison of linear and macrocyclic compound libraries as a source of protein ligandsState-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches.Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.Lost in chemical space? Maps to support organometallic catalysis.cis-Diastereoselective synthesis of chroman-fused tetralins as B-ring-modified analogues of brazilinNatural product driven diversity via skeletal remodeling of caryophyllene β-lactam.Catalysis of Cascade and Multicomponent Reactions of Carbonyl Compounds and CH Acids by Electricity.Biomimetic Assembly Lines Producing Natural Product Analogs: Strategies from a Versatile Manifold to Skeletally Diverse Scaffolds.C-H Activation and Alkyne Annulation via Automatic or Intrinsic Directing Groups: Towards High Step Economy.Modular Bi-Directional One-Pot Strategies for the Diastereoselective Synthesis of Structurally Diverse Collections of Constrained β-Carboline-Benzoxazepines.Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine.Strategies to advance drug discovery in rare monogenic intellectual disability syndromes.Ni-Catalyzed Stannylation of Aryl Esters via C-O Bond Cleavage.LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors.Photoinduced Remote Functionalisations by Iminyl Radical Promoted C-C and C-H Bond Cleavage Cascades.Emulating Natural Product Conformation by Cooperative, Non-Covalent Fluorine Interactions.Diverse display of non-covalent interacting elements using pyrimidine-embedded polyheterocycles.Regioselective alkylation of 1,3,4,5-tetrahydrobenzo[d]azepin-2-one and biological evaluation of the resulting alkylated products as potentially selective [Formula: see text] agonists.A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-Distortion
P2860
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P2860
Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Privileged structures: efficie ...... cally relevant chemical spaces
@ast
Privileged structures: efficie ...... cally relevant chemical spaces
@en
Privileged structures: efficie ...... cally relevant chemical spaces
@nl
type
label
Privileged structures: efficie ...... cally relevant chemical spaces
@ast
Privileged structures: efficie ...... cally relevant chemical spaces
@en
Privileged structures: efficie ...... cally relevant chemical spaces
@nl
prefLabel
Privileged structures: efficie ...... cally relevant chemical spaces
@ast
Privileged structures: efficie ...... cally relevant chemical spaces
@en
Privileged structures: efficie ...... cally relevant chemical spaces
@nl
P3181
P356
P1476
Privileged structures: efficie ...... cally relevant chemical spaces
@en
P2093
Heejun Kim
Jonghoon Kim
P304
14629-14638
P3181
P356
10.1021/JA508343A
P407
P577
2014-10-22T00:00:00Z