State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.
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The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular DiseasesVirtual Screening Approaches towards the Discovery of Toll-Like Receptor ModulatorsCytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.Fragment-Based Protein-Protein Interaction Antagonists of a Viral Dimeric ProteaseSmall Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal TransductionGlutamine Synthetase Drugability beyond Its Active Site: Exploring Oligomerization Interfaces and Pockets.Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.In silico identification of essential proteins in Corynebacterium pseudotuberculosis based on protein-protein interaction networksScreening-based approaches to identify small molecules that inhibit protein-protein interactions.Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3.Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.Side-Chain Conformational Preferences Govern Protein-Protein Interactions.A small-molecule inhibitor targeting the AURKC-IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells.Mapping Protein-Protein Interactions of the Resistance-Related Bacterial Zeta Toxin-Epsilon Antitoxin Complex (ε₂ζ₂) with High Affinity Peptide Ligands Using Fluorescence Polarization.Inhibition of HSP90 sensitizes a novel Raf/ERK dual inhibitor CY-9d in triple-negative breast cancer cells.A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53.Targeting Unoccupied Surfaces on Protein-Protein Interfaces.Several inhibitors of the Plk1 Polo-Box Domain turn out to be non-specific protein alkylators.Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.
P2860
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P2860
State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@ast
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@en
type
label
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@ast
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@en
prefLabel
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@ast
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@en
P2093
P2860
P356
P1476
State-of-the-art strategies fo ...... by small-molecule inhibitors.
@en
P2093
Chunquan Sheng
Guoqiang Dong
Wannian Zhang
Zhenyuan Miao
P2860
P304
P356
10.1039/C5CS00252D
P577
2015-08-06T00:00:00Z