p62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress
about
The ubiquitin proteasome system and myocardial ischemiaClusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalp62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradationAutophagic-lysosomal inhibition compromises ubiquitin-proteasome system performance in a p62 dependent manner in cardiomyocytesThe ubiquitin proteasome system in human cardiomyopathies and heart failure.p62 improves AD-like pathology by increasing autophagyTubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway.A strategy to combine pathway-targeted low toxicity drugs in ovarian cancerUbiquitin receptors and protein quality controlDefects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings.Lipopolysaccharide stimulates p62-dependent autophagy-like aggregate clearance in hepatocytes.Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency.Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation.Fibroblast autophagy in fibrotic disorders.Posttranslational modification and quality control.Autophagy and ubiquitination in cardiovascular diseases.To beat or not to beat: degradation of Cx43 imposes the heart rhythm.Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation.Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.Autophagy modulation: a potential therapeutic approach in cardiac hypertrophy.Effect of treadmill exercise on skeletal muscle autophagy in rats with obesity induced by a high-fat diet.The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity.Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor.Roles of Autophagy in Ischemic Heart Diseases and the Modulatory Effects of Chinese Herbal Medicine.Phospholamban p.Arg14del cardiomyopathy is characterized by phospholamban aggregates, aggresomes, and autophagic degradation.Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis.Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel
P2860
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P2860
p62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress
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2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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name
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@ast
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@en
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@nl
type
label
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@ast
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@en
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@nl
prefLabel
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@ast
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@en
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@nl
P2860
P3181
P1476
p62 Stages an interplay betwee ...... nse against proteotoxic stress
@en
P2093
P2860
P304
P3181
P356
10.1016/J.TCM.2012.05.015
P407
P50
P577
2011-11-01T00:00:00Z