p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death - Test2 - elhamkhani - TriplyDB

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

http://www.wikidata.org/entity/Q29547297

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease Subversion of autophagy in adherent invasive Escherichia coli-infected neutrophils induces inflammation and cell death Guidelines for the use and interpretation of assays for monitoring autophagy Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A comprehensive glossary of autophagy-related molecules and processes (2nd edition)Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy Endogenous HMGB1 regulates autophagy p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1 Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation Autophagy in lysosomal storage disorders Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling The Cvt pathway as a model for selective autophagy Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model Autophagy and NF-kappaB: fight for fate Autophagy signal transduction by ATG proteins: from hierarchies to networks

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P2860

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

http://www.wikidata.org/entity/Q29547297

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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type

label

p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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p62/SQSTM1 forms protein aggre ...... huntingtin-induced cell death

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Brech A

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Lamark T

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Outzen H

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Overvatn A

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Perander M

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P2860

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

Structure and functional properties of the ubiquitin binding protein p62

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

SUMO modification of Huntingtin and Huntington's disease pathology

The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat

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10.1083/JCB.200507002

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4

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171

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Harald Stenmark

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2005-11-21T00:00:00Z

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7480970

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