Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway - Test2 - elhamkhani - TriplyDB

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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Dissecting the genomic complexity underlying medulloblastoma Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy Systems biology of cisplatin resistance: past, present and future Two 4N cell-cycle arrests contribute to cisplatin-resistance Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention.p21-Activated kinase 5 affects cisplatin-induced apoptosis and proliferation in hepatocellular carcinoma cells.p53: guardian of ploidy Illicit survival of cancer cells during polyploidization and depolyploidization.Cell death signaling and anticancer therapy Selective killing of p53-deficient cancer cells by SP600125.Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells Medulloblastomics: the end of the beginning.Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer.Abnormal mitosis triggers p53-dependent cell cycle arrest in human tetraploid cells.Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia.Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines.Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2.RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel.Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization.Losmapimod: A Novel Clinical Drug to Overcome Gefitinib-Resistance.Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.Preferential killing of p53-deficient cancer cells by reversine.

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Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

http://www.wikidata.org/entity/Q27302281

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2007 nî lūn-bûn

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2007 թուականին հրատարակուած գիտական յօդուած

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2007 թվականին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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type

label

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

@ast

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

@en

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

@nl

prefLabel

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

@ast

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

@en

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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JOURNAL.PONE.0001337

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Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

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Ken A Olaussen

http://www.w3.org/2001/XMLSchema#string

Lisa Nanty

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Maria Castedo

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Michelle Prudhomme

http://www.w3.org/2001/XMLSchema#string

Philippe Dessen

http://www.w3.org/2001/XMLSchema#string

Roy M Golsteyn

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Sonia Vivet

http://www.w3.org/2001/XMLSchema#string

Vladimir Lazar

http://www.w3.org/2001/XMLSchema#string

P2860

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

Chk2 activates E2F-1 in response to DNA damage

Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Mechanisms of apoptosis induction by the HIV-1 envelope

From polyploidy to aneuploidy, genome instability and cancer

Chk1 inhibitors for novel cancer treatment

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e1337

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scholarly article

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10.1371/JOURNAL.PONE.0001337

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12

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Lorenzo Galluzzi

Laura Senovilla

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2007-01-01T00:00:00Z

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5690626

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18159231

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2131784

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