Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.
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Wiskott-Aldrich syndrome protein controls antigen-presenting cell-driven CD4+ T-cell motility by regulating adhesion to intercellular adhesion molecule-1Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoGeneration of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeletonThe multiple faces of leukocyte interstitial migrationCongenital defects in neutrophil dynamicsActin cytoskeletal defects in immunodeficiencyChemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrestDOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memorySkap2 is required for β2 integrin-mediated neutrophil recruitment and functions.Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis.Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking.Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis.The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signalingCdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubulesThe small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation.The Lung is a Host Defense Niche for Immediate Neutrophil-Mediated Vascular Protection.Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo.Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets.Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity stateWiskott-Aldrich syndrome: a comprehensive review.Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow.Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motilityNeutrophil adhesion and activation under flow.The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans.Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in miceDendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndromeAutoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis.Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation.Mechanisms of neutrophil transendothelial migrationThe Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile InflammationThe ins and outs of leukocyte integrin signaling.Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationTyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function.Inflammatory bowel diseases in patients with adaptive and complement immunodeficiency disorders.
P2860
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P2860
Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Impaired integrin-dependent fu ...... t murine and human neutrophils
@nl
Impaired integrin-dependent fu ...... murine and human neutrophils.
@ast
Impaired integrin-dependent fu ...... murine and human neutrophils.
@en
type
label
Impaired integrin-dependent fu ...... t murine and human neutrophils
@nl
Impaired integrin-dependent fu ...... murine and human neutrophils.
@ast
Impaired integrin-dependent fu ...... murine and human neutrophils.
@en
prefLabel
Impaired integrin-dependent fu ...... t murine and human neutrophils
@nl
Impaired integrin-dependent fu ...... murine and human neutrophils.
@ast
Impaired integrin-dependent fu ...... murine and human neutrophils.
@en
P2093
P2860
P1433
P1476
Impaired integrin-dependent fu ...... murine and human neutrophils.
@en
P2093
Chad E Green
Clifford A Lowell
Diane Wara
Hong Zhang
Melissa R Sarantos
Scott I Simon
Ulrich Y Schaff
Yongmei Hu
P2860
P304
P356
10.1016/J.IMMUNI.2006.06.014
P407
P577
2006-08-10T00:00:00Z