Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
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ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivoIdentifying the rules of engagement enabling leukocyte rolling, activation, and adhesionuPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxisCrossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during ExtravasationThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationVav family exchange factors: an integrated regulatory and functional viewImpaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.Targeting leukocyte integrins in human diseasesA point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunityIntegrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifsNeutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infectionThe Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanineNeutrophils and immunity: challenges and opportunitiesNeutrophil cell surface receptors and their intracellular signal transduction pathways.c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity.Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic MiceGalphai2 is required for chemokine-induced neutrophil arrest.Mechanisms and consequences of neutrophil interaction with the endothelium.Rho GEF Lsc is required for normal polarization, migration, and adhesion of formyl-peptide-stimulated neutrophilsVav3-deficient mice exhibit a transient delay in cerebellar developmentGuanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edgeMigrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium fluxAn extracellular matrix-based mechanism of rapid neutrophil extracellular trap formation in response to Candida albicans.Vav Guanine nucleotide exchange factors regulate atherosclerotic lesion development in mice.Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculatureVAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humansNeutrophil adhesion and activation under flow.Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1A novel network profiling analysis reveals system changes in epithelial-mesenchymal transitionProline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fateVav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters.Vav/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis.Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs.A role of kindlin-3 in integrin αMβ2 outside-in signaling and the Syk-Vav1-Rac1/Cdc42 signaling axisTROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling.The β-glucan receptor Dectin-1 activates the integrin Mac-1 in neutrophils via Vav protein signaling to promote Candida albicans clearanceThe expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.
P2860
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P2860
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
@nl
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@ast
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@en
type
label
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
@nl
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@ast
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@en
prefLabel
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
@nl
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@ast
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@en
P2093
P2860
P921
P356
P1476
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
@en
P2093
Joan S Brugge
Julie L Wilsbacher
M Angelica Martinez Gakidis
Sheri L Moores
Tanya Mayadas
Timothy Olson
Wojciech Swat
Xavier Cullere
P2860
P304
P356
10.1083/JCB.200404166
P407
P577
2004-07-12T00:00:00Z