Initiation of T cell signaling by CD45 segregation at 'close contacts'
about
Recent advances in T-cell engineering for use in immunotherapyMembrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages.Tapping out a mechanical code for T cell triggeringCatch Bonds at T Cell Interfaces: Impact of Surface Reorganization and Membrane Fluctuations.The Activating C-type Lectin-like Receptor NKp65 Signals through a Hemi-immunoreceptor Tyrosine-based Activation Motif (hemITAM) and Spleen Tyrosine Kinase (Syk).Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond.Phagocytosis: A Fundamental Process in Immunity.Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering.Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherinMacrophages: micromanagers of antagonistic signaling nanoclusters.Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity.Localizing order to boost signaling.Molecular basis of human CD22 function and therapeutic targeting.In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.The "Phagocytic Synapse" and Clearance of Apoptotic Cells.Introducing Membrane Charge and Membrane Potential to T Cell Signaling.Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation.Nanobody Based Dual Specific CARs.New Chimeric Antigen Receptor Design for Solid Tumors.Nanoscale kinetic segregation of TCR and CD45 in engaged microvilli facilitates early T cell activation.PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations.A Protein Expression Toolkit for Studying Signaling in T Cells.TCR Signaling: Mechanisms of Initiation and Propagation.High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation.Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug deliveryNew tricks for old targets: Anti-CTLA-4 antibodies re-envisioned for cancer immunotherapyT Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 EngagementIsolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC BindingDimensions and Interactions of Large T-Cell Surface ProteinsMembrane Ultrastructure and T Cell ActivationFull control of ligand positioning reveals spatial thresholds for T cell receptor triggeringHydrodynamic trapping measures the interaction between membrane-associated moleculesInterCells: A Generic Monte-Carlo Simulation of Intercellular Interfaces Captures Nanoscale Patterning at the Immune Synapse
P2860
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P2860
Initiation of T cell signaling by CD45 segregation at 'close contacts'
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@ast
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@en
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@nl
type
label
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@ast
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@en
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@nl
prefLabel
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@ast
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@en
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Initiation of T cell signaling by CD45 segregation at 'close contacts'
@en
P2093
A Radu Aricescu
Christian Siebold
David Klenerman
Elizabeth Huang
Karl Harlos
Simon J Davis
Steven F Lee
Veronica T Chang
P2860
P304
P3181
P356
10.1038/NI.3392
P407
P50
P577
2016-05-01T00:00:00Z