Large-scale structural analysis of the classical human protein tyrosine phosphatome
about
Catalytically active membrane-distal phosphatase domain of receptor protein-tyrosine phosphatase alpha is required for Src activationRegulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domainShepherding AKT and androgen receptor by Ack1 tyrosine kinaseStructure and function of the intracellular region of the plexin-b1 transmembrane receptorReceptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesisActivation of Src and transformation by an RPTPα splice mutant found in human tumoursHistone recognition and large-scale structural analysis of the human bromodomain familyDephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absentTumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinasesZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppressionThe human phosphatase interactome: An intricate family portraitA novel molecular diagnostic of glioblastomas: detection of an extracellular fragment of protein tyrosine phosphatase muProtein phosphatases and Alzheimer's diseaseSmall molecule tools for functional interrogation of protein tyrosine phosphatasesInitiation of T cell signaling by CD45 segregation at 'close contacts'Dynamic recruitment of protein tyrosine phosphatase PTPD1 to EGF stimulation sites potentiates EGFR activationCrystal Structure of the Human Lymphoid Tyrosine Phosphatase Catalytic Domain: Insights into Redox Regulation,Multidentate Small-Molecule Inhibitors of Vaccinia H1-Related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer CellsThe protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)The Trypanosoma brucei Life Cycle Switch TbPTP1 Is Structurally Conserved and Dephosphorylates the Nucleolar Protein NOPP44/46Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E LoopStructure and Substrate Recognition of the Staphylococcus aureus Protein Tyrosine Phosphatase PtpAA Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 DiabetesStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionA Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune DiseasesEvolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate SpecificitiesDiverse Levels of Sequence Selectivity and Catalytic Efficiency of Protein-Tyrosine PhosphatasesStructural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substratesThe family-wide structure and function of human dual-specificity protein phosphatasesReciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formationSelective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivoModulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injuryInhibition of BET bromodomains as a therapeutic strategy for cancer drug discoveryCharacterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cellsActivation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discoveryExploring protein structure and dynamics through a project-oriented biochemistry laboratory module.Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.
P2860
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P248
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P2860
Large-scale structural analysis of the classical human protein tyrosine phosphatome
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@ast
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en-gb
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@nl
type
label
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@ast
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en-gb
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@nl
altLabel
Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome
@en
prefLabel
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@ast
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en-gb
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Large-scale structural analysis of the classical human protein tyrosine phosphatome
@en
P2093
Emilie Ugochukwu
Ivan Alfano
Nicola A Burgess-Brown
Oliver N F King
P2860
P304
P3181
P356
10.1016/J.CELL.2008.11.038
P407
P577
2009-01-23T00:00:00Z