A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
about
The cell biology of malaria infection of mosquito: advances and opportunitiesPhosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion.Spatial localisation of actin filaments across developmental stages of the malaria parasiteA unique Kelch domain phosphatase in Plasmodium regulates ookinete morphology, motility and invasionDisruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assayA unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasionGenome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiationMorphogenesis of Plasmodium zoites is uncoupled from tensile strength.Cyclic GMP balance is critical for malaria parasite transmission from the mosquito to the mammalian hostThe development of malaria parasites in the mosquito midgutTowards genome-wide experimental genetics in the in vivo malaria model parasite Plasmodium bergheiDevelopment of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug targetPhosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasitescAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite TransmissionA Putative Non-Canonical Ras-Like GTPase from P. falciparum: Chemical Properties and Characterization of the ProteinPlasmodium alveolins possess distinct but structurally and functionally related multi-repeat domainsSpatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinaseAn ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmissionPlasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in MosquitoesComparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates.Distinct signalling pathways control Toxoplasma egress and host-cell invasionVital functions of the malarial ookinete protein, CTRP, reside in the A domains.Mitochondrial ATP synthase is dispensable in blood-stage Plasmodium berghei rodent malaria but essential in the mosquito phaseThe malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony.A scalable pipeline for highly effective genetic modification of a malaria parasite.Activity of a trisubstituted pyrrole in inhibiting sporozoite invasion and blocking malaria infection.The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmissionGenome wide in silico analysis of Plasmodium falciparum phosphatome.Genetic basis for phenotypic differences between different Toxoplasma gondii type I strainsQuantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility.Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite.Critical role for heat shock protein 20 (HSP20) in migration of malarial sporozoites.The alveolin IMC1h is required for normal ookinete and sporozoite motility behaviour and host colonisation in Plasmodium berghei.A Plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mRNAs.The role of cGMP signalling in regulating life cycle progression of Plasmodium.Evolution of apicomplexan secretory organelles.A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle.Culture adaptation of malaria parasites selects for convergent loss-of-function mutants.Phylogenetic profiles of all membrane transport proteins of the malaria parasite highlight new drug targetsCyclic nucleotide signalling in malaria parasites.
P2860
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P2860
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@ast
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@en
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@nl
type
label
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@ast
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@en
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@nl
prefLabel
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@ast
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@en
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite
@en
P2093
Andrew P Waters
Cathy J Taylor
Claudia Bex
David Goulding
Rebecca Schepers
Robert W Moon
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1000599
P407
P577
2009-09-01T00:00:00Z