Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites
about
The cell biology of malaria infection of mosquito: advances and opportunitiesThe calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium sppPhosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion.Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.Recent advances in malaria genomics and epigenomicsThe development of malaria parasites in the mosquito midgutCrystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egressPlasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite DeathSerum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondiiPlasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondiiMultiple short windows of calcium-dependent protein kinase 4 activity coordinate distinct cell cycle events during Plasmodium gametogenesis.The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysisPlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites.Associations between Season and Gametocyte Dynamics in Chronic Plasmodium falciparum Infections.Lytic Cycle of Toxoplasma gondii: 15 Years Later.Post-translational protein modifications in malaria parasites.Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.Calcium signalling in malaria parasites.A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa.Genomics of apicomplexan parasites.Fluorescent Protein-photoprotein Fusions and Their Applications in Calcium Imaging.Plasmodium falciparum apicoplast and its transcriptional regulation through calcium signaling.Signaling Strategies of Malaria Parasite for Its Survival, Proliferation, and Infection during Erythrocytic Stage.A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii.Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium.Invasion of hepatocytes by Plasmodium sporozoites requires cGMP-dependent protein kinase and calcium dependent protein kinase 4.Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage.Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation.Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development.Analysis of Ca2+ mediated signaling regulating Toxoplasma infectivity reveals complex relationships between key molecules.Cyclic nucleotide signalling in malaria parasites.Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the Toxoplasma Micronemes.Potential Sabotage of Host Cell Physiology by Apicomplexan Parasites for Their Survival Benefits.PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection.A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress.Post-translational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies.Crosstalk between PKA and PKG controls pH-dependent host cell egress of Toxoplasma gondii.A forward genetic screen identifies a negative regulator of rapid Ca2+-dependent cell egress (MS1) in the intracellular parasite Toxoplasma gondii.Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell.
P2860
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P2860
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites
description
2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@ast
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@en
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@nl
type
label
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@ast
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@en
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@nl
prefLabel
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@ast
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@en
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Phosphoinositide metabolism li ...... ife cycle of malaria parasites
@en
P2093
Eloise Thompson
Katrin Volkmann
Mark O Collins
Sarah Sebastian
Terry K Smith
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001806
P407
P50
P577
2014-03-01T00:00:00Z