A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma
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Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomesRNAi screening in Drosophila cells and in vivo.Drosophila melanogaster as a model organism for Alzheimer's disease.Investigating the role of RIO protein kinases in Caenorhabditis elegans.Flatworms have lost the right open reading frame kinase 3 gene during evolution.High Expression of RIOK2 and NOB1 Predict Human Non-small Cell Lung Cancer Outcomes.Probing the enigma: unraveling glial cell biology in invertebrates.Transcriptional regulation of the stress response by mTOR.The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior.The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells.The Link between Protein Kinase CK2 and Atypical Kinase Rio1.Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1Drosophila PS2 and PS3 integrins play distinct roles in retinal photoreceptors-glia interactions.Structural and developmental expression of Ss-riok-2, an RIO protein kinase encoding gene of Strongyloides stercoralis.mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.The RIO protein kinase-encoding gene Sj-riok-2 is involved in key reproductive processes in Schistosoma japonicum.A metabolic function of FGFR3-TACC3 gene fusions in cancer.Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.Identification of genes involved in the biology of atypical teratoid/rhabdoid tumours using Drosophila melanogaster.Modelling Cooperative Tumorigenesis in Drosophila.RNA Interference (RNAi) Screening in Drosophila.RIOK-1 Is a Suppressor of the p38 MAPK Innate Immune Pathway in Caenorhabditis elegans.
P2860
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P2860
A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma
description
2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@ast
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@en
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@nl
type
label
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@ast
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@en
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@nl
prefLabel
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@ast
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@en
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@nl
P2093
P2860
P921
P3181
P1433
P1476
A kinome-wide RNAi screen in D ...... -Akt signaling in glioblastoma
@en
P2093
Akio Iwanami
German G Gomez
Huijun Yang
Ivan Babic
Jill Wykosky
John B Thomas
Paul S Mischel
Renee D Read
Scott R Vandenberg
Webster K Cavenee
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1003253
P407
P577
2013-01-01T00:00:00Z