Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations
about
Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencingMouse Genome Informatics (MGI): reflecting on 25 yearsDeep sequencing strategies for mapping and identifying mutations from genetic screensPhenotypic instability between the near isogenic substrains BALB/cJ and BALB/cByJ.Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.Dissecting mammalian immunity through mutation.Pilot study of large-scale production of mutant pigs by ENU mutagenesisLarge-scale identification of chemically induced mutations in Drosophila melanogaster.The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease.Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndromeMouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives.Ion Torrent sequencing for conducting genome-wide scans for mutation mapping analysis.Real-time resolution of point mutations that cause phenovariance in mice.Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.Variant mapping and mutation discovery in inbred mice using next-generation sequencingMutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection.Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines.Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice.Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse
P2860
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P2860
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
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2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Unlocking the bottleneck in fo ...... to isolate causative mutations
@ast
Unlocking the bottleneck in fo ...... to isolate causative mutations
@en
Unlocking the bottleneck in fo ...... to isolate causative mutations
@nl
type
label
Unlocking the bottleneck in fo ...... to isolate causative mutations
@ast
Unlocking the bottleneck in fo ...... to isolate causative mutations
@en
Unlocking the bottleneck in fo ...... to isolate causative mutations
@nl
prefLabel
Unlocking the bottleneck in fo ...... to isolate causative mutations
@ast
Unlocking the bottleneck in fo ...... to isolate causative mutations
@en
Unlocking the bottleneck in fo ...... to isolate causative mutations
@nl
P2093
P2860
P50
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Unlocking the bottleneck in fo ...... to isolate causative mutations
@en
P2093
Andrew J Rimmer
Belinda Whittle
Carla M Roots
Christopher C Goodnow
Edward M Bertram
Lisa A Miosge
Michelle M Simon
Richard J Cornall
Steve D M Brown
Tanya L Crockford
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P304
P3181
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10.1371/JOURNAL.PGEN.1003219
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P577
2013-01-01T00:00:00Z