about
8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineageThe bonobo genome compared with the chimpanzee and human genomesInsights into hominid evolution from the gorilla genome sequenceComparative and demographic analysis of orang-utan genomesFunctionality or transcriptional noise? Evidence for selection within long noncoding RNAsBayesian coestimation of phylogeny and sequence alignmentGenome-wide identification of human functional DNA using a neutral indel modelUnlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutationsRecessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor developmentStampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence readsA new isolation with migration model along complete genomes infers very different divergence processes among closely related great ape speciesMassive turnover of functional sequence in human and other mammalian genomesAccelerated evolution of the Prdm9 speciation gene across diverse metazoan taxaInvestigating selection on viruses: a statistical alignment approach.Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain.Dindel: accurate indel calls from short-read data.Genome assembly quality: assessment and improvement using the neutral indel modelEstimating divergence time and ancestral effective population size of Bornean and Sumatran orangutan subspecies using a coalescent hidden Markov model.The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.Accurate reconstruction of insertion-deletion histories by statistical phylogenetics.Identification of antigen-specific B cell receptor sequences using public repertoire analysis.Improved workflows for high throughput library preparation using the transposome-based Nextera systemNovel type IV secretion system involved in propagation of genomic islands.BCR repertoire sequencing: different patterns of B-cell activation after two Meningococcal vaccines.In-Depth Assessment of Within-Individual and Inter-Individual Variation in the B Cell Receptor Repertoire.Factors influencing success of clinical genome sequencing across a broad spectrum of disordersAnalysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody SequencesA fine-scale chimpanzee genetic map from population sequencing.Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applicationsSignatures of adaptive evolution within human non-coding sequence.The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes.Evolution of primate gene expression: drift and corrective sweeps?B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation.HMMoC--a compiler for hidden Markov models.The Diversity and Molecular Evolution of B-Cell Receptors during Infection.scrm: efficiently simulating long sequences using the approximated coalescent with recombinationCSN and CAVA: variant annotation tools for rapid, robust next-generation sequencing analysis in the clinical setting.OpEx - a validated, automated pipeline optimised for clinical exome sequence analysis.A Phylogenetic Codon Substitution Model for Antibody Lineages.Erratum to: B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation.
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Gerton Lunter
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P21
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0000-0002-3798-2058