Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
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Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as TherapyKetamine, Transcranial Magnetic Stimulation, and Depression Specific Yoga and Mindfulness Based Cognitive Therapy in Management of Treatment Resistant Depression: Review and Some Data on EfficacyPotential of Glutamate-Based Drug Discovery for Next Generation AntidepressantsRapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptorsR-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effectsGlial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats.Previous Ketamine Produces an Enduring Blockade of Neurochemical and Behavioral Effects of Uncontrollable StressLongitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal CortexSynaptic Ensemble Underlying the Selection and Consolidation of Neuronal Circuits during Learning.KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.Laminar and Cellular Distribution of Monoamine Receptors in Rat Medial Prefrontal CortexPosterior Orbitofrontal and Anterior Cingulate Pathways to the Amygdala Target Inhibitory and Excitatory Systems with Opposite Functions.Differential Patterns of Subcortical Activity Evoked by Glial GLT-1 Blockade in Prelimbic and Infralimbic Cortex: Relationship to Antidepressant-Like Effects in Rats.Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine.BDNF release and signaling are required for the antidepressant actions of GLYX-13.Effects of a single bilateral infusion of R-ketamine in the rat brain regions of a learned helplessness model of depression.Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.Activity in the ventral medial prefrontal cortex is necessary for the therapeutic effects of extinction in rats.Role of 5-HT1A receptor stimulation in the medial prefrontal cortex in the sustained antidepressant effects of ketamine.Optogenetic Activation of the Infralimbic Cortex Suppresses the Return of Appetitive Pavlovian-Conditioned Responding Following Extinction.GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.Orphan receptor GPR158 controls stress-induced depression.Ketamine accelerates fear extinction via mTORC1 signaling.Ventral CA3 Activation Mediates Prophylactic Ketamine Efficacy Against Stress-Induced Depressive-like Behavior.Convergent Mechanisms Underlying Rapid Antidepressant Action.Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females.Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model.Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-KetamineEradicating Suicide at Its Roots: Preclinical Bases and Clinical Evidence of the Efficacy of Ketamine in the Treatment of Suicidal Behaviors
P2860
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P2860
Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Optogenetic stimulation of inf ...... stained antidepressant actions
@nl
Optogenetic stimulation of inf ...... tained antidepressant actions.
@ast
Optogenetic stimulation of inf ...... tained antidepressant actions.
@en
type
label
Optogenetic stimulation of inf ...... stained antidepressant actions
@nl
Optogenetic stimulation of inf ...... tained antidepressant actions.
@ast
Optogenetic stimulation of inf ...... tained antidepressant actions.
@en
prefLabel
Optogenetic stimulation of inf ...... stained antidepressant actions
@nl
Optogenetic stimulation of inf ...... tained antidepressant actions.
@ast
Optogenetic stimulation of inf ...... tained antidepressant actions.
@en
P2093
P2860
P356
P1476
Optogenetic stimulation of inf ...... stained antidepressant actions
@en
P2093
Alexandra Thomas
Benjamin B Land
Eric S Wohleb
George K Aghajanian
Manabu Fuchikami
Ronald S Duman
Rongjian Liu
P2860
P304
P356
10.1073/PNAS.1414728112
P407
P577
2015-06-08T00:00:00Z