R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
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Ketamine enantiomers in the rapid and sustained antidepressant effectsComparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depressionKetamine's antidepressant action: beyond NMDA receptor inhibitionRole of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in miceIntake of 7,8-Dihydroxyflavone During Juvenile and Adolescent Stages Prevents Onset of Psychosis in Adult Offspring After Maternal Immune ActivationNMDAR inhibition-independent antidepressant actions of ketamine metabolites.Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine.Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with KetamineNMDA Receptors Regulate the Structural Plasticity of Spines and Axonal Boutons in Hippocampal Interneurons.Antidepressant effects of ketamine and the roles of AMPA glutamate receptors and other mechanisms beyond NMDA receptor antagonismInvestigational drugs for treating major depressive disorder.Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut-microbiota-brain axisBeyond serotonin: newer antidepressants in the future.Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress.Depression-like phenotype by deletion of α7 nicotinic acetylcholine receptor: Role of BDNF-TrkB in nucleus accumbens.Ketamine: NMDA Receptors and Beyond.Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model.Reduction of dopamine D2/3 receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys.Treating to target in major depressive disorder: response to remission to functional recovery.New Treatment Strategies of Depression: Based on Mechanisms Related to Neuroplasticity.Targeting glutamate signalling in depression: progress and prospects.Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant.Glutamate-Based Drug Discovery for Novel Antidepressants.On the Eve of Upgrading Antidepressants: (R)-Ketamine and Its Metabolites.Administration of ketamine for unipolar and bipolar depression.Regional differences in the expression of brain-derived neurotrophic factor (BDNF) pro-peptide, proBDNF and preproBDNF in the brain confer stress resilience.Regional differences in dendritic spine density confer resilience to chronic social defeat stress.Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling.Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype.Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation.Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine.Breaking Sad: Unleashing the Breakthrough Potential of Ketamine's Rapid Antidepressant Effects.Possible role of the gut microbiota-brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model.Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model.Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior.Special Topic on Mental Health and Addiction.Intracellular Signaling Pathways Involved in (S)- and (R)-Ketamine Antidepressant Actions.Subanesthetic ketamine decreases the incentive-motivational value of reward-related cues.Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit.Effects of a single bilateral infusion of R-ketamine in the rat brain regions of a learned helplessness model of depression.
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R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@ast
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@en
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@nl
type
label
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@ast
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@en
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@nl
prefLabel
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@ast
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@en
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@nl
P2093
P2860
P3181
P356
P1476
R-ketamine: a rapid-onset and ...... t psychotomimetic side effects
@en
P2093
P2860
P2888
P3181
P356
10.1038/TP.2015.136
P407
P577
2015-09-01T00:00:00Z
P5875
P6179
1030285572