Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.
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Behavioral phenotypes of genetic mouse models of autism.Treatment of neurodevelopmental disorders in adulthoodTherapeutic approaches for shankopathiesBehavioral and Neuroanatomical Phenotypes in Mouse Models of AutismA neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in miceAbsence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorderEvaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autismLetting a typical mouse judge whether mouse social interactions are atypicalProsocial effects of oxytocin in two mouse models of autism spectrum disordersTherapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of AutismAMPAKINE enhancement of social interaction in the BTBR mouse model of autismEffect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism.GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of AutismThe BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactionsTranslational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Reversal of social deficits by subchronic oxytocin in two autism mouse models.Impairment of translation in neurons as a putative causative factor for autismSocial communication in mice--are there optimal cage conditions?Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice.Sensory integration in mouse insular cortex reflects GABA circuit maturationRepetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2.Influence of stimulant-induced hyperactivity on social approach in the BTBR mouse model of autismTranslational animal models of autism and neurodevelopmental disorders.Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging.Low home cage social behaviors in BTBR T+tf/J mice during juvenile development.Acetylcholine elevation relieves cognitive rigidity and social deficiency in a mouse model of autism.Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits.Autism Spectrum Disorders and Schizophrenia Spectrum Disorders: Excitation/Inhibition Imbalance and Developmental Trajectories.Long-term memory deficits are associated with elevated synaptic ERK1/2 activation and reversed by mGluR5 antagonism in an animal model of autism.Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismMapping pathological phenotypes in reelin mutant mice.Development of allosteric modulators of GPCRs for treatment of CNS disordersFragile X syndrome: clinical, cytogenetic and molecular screening among autism spectrum disorder children in Indonesia.Long-term exposure to intranasal oxytocin in a mouse autism model.Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism
P2860
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P2860
Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.
description
2012 nî lūn-bûn
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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Negative allosteric modulation ...... cits in mouse models of autism
@nl
Negative allosteric modulation ...... its in mouse models of autism.
@ast
Negative allosteric modulation ...... its in mouse models of autism.
@en
type
label
Negative allosteric modulation ...... cits in mouse models of autism
@nl
Negative allosteric modulation ...... its in mouse models of autism.
@ast
Negative allosteric modulation ...... its in mouse models of autism.
@en
prefLabel
Negative allosteric modulation ...... cits in mouse models of autism
@nl
Negative allosteric modulation ...... its in mouse models of autism.
@ast
Negative allosteric modulation ...... its in mouse models of autism.
@en
P2093
P2860
P3181
P1476
Negative allosteric modulation ...... its in mouse models of autism.
@en
P2093
Daniel G Smith
Deborah L Smith
Dianne K Bryce
Jacqueline N Crawley
Jill L Silverman
Kari Fonseca
Michael N Karras
Sarah M Turner
Seda S Tolu
Stacey J Sukoff Rizzo
P2860
P304
P3181
P356
10.1126/SCITRANSLMED.3003501
P407
P577
2012-04-01T00:00:00Z