Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity - Test2 - elhamkhani - TriplyDB

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

http://www.wikidata.org/entity/Q27333772

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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation Micro- and nanoscale engineering of cell signaling Regulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasm Linking form to function: Biophysical aspects of artificial antigen presenting cell design Mechanical regulation of T-cell functions A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.A role for rebinding in rapid and reliable T cell responses to antigen T cell receptor triggering by force.The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Perspectives for computer modeling in the study of T cell activation Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells.Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection.Distribution and dynamics of rat basophilic leukemia immunoglobulin E receptors (FcepsilonRI) on planar ligand-presenting surfaces.Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.How the immune system talks to itself: the varied role of synapses Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.TCR triggering by pMHC ligands tethered on surfaces via poly(ethylene glycol) depends on polymer length.Ligand-mediated friction determines morphodynamics of spreading T cells Piecing together the family portrait of TCR-CD3 complexes.The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility Probing orientational behavior of MHC class I protein and lipid probes in cell membranes by fluorescence polarization-resolved imaging.Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells.A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ.Substrate rigidity regulates human T cell activation and proliferation Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network.Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism.Functional development of the T cell receptor for antigen Stochastic effects and bistability in T cell receptor signaling Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology.An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a Change we can believe in--of the conformational type. Workshop on the Initiation of Antigen Receptor Signaling T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens.Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination T cell activation is determined by the number of presented antigens.Antibody-peptide-MHC fusion conjugates target non-cognate T cells to kill tumour cells.

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P2860

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

http://www.wikidata.org/entity/Q27333772

description

2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

article scientifique (publié 2008-02)

@fr

articolo scientifico (pubblicato il 2008-02)

@it

artigo científico (publicado na 2008-02)

@pt

artículu científicu espublizáu en 2008

@ast

im Februar 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: February 2008)

@en

vedecký článok (publikovaný 2008-02)

@sk

videnskabelig artikel (udgivet 2008-02)

@da

name

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@ast

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@en

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@nl

type

label

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@ast

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@en

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@nl

prefLabel

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@ast

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@en

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@nl

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JOURNAL.PBIO.0060043

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P1476

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

@en

P2093

Kim A Sharp

http://www.w3.org/2001/XMLSchema#string

Paul A Janmey

http://www.w3.org/2001/XMLSchema#string

Terri H Finkel

http://www.w3.org/2001/XMLSchema#string

Zhengyu Ma

http://www.w3.org/2001/XMLSchema#string

P2860

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

The crystal structure of a T cell receptor in complex with peptide and MHC class II

A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

Crystal structure of a T cell receptor bound to an allogeneic MHC molecule

Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

P304

e43

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scholarly article

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10.1371/JOURNAL.PBIO.0060043

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P407

P433

2

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6

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2008-02-01T00:00:00Z

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5548452

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P698

18303949

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P932

2253636

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