Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice.
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Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B PolymorphismsMouse models to study dengue virus immunology and pathogenesisRecombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys.West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacyA tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient micePaired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.Characterization of a small plaque variant of West Nile virus isolated in New York in 2000Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicityA Single Point Mutation in Nonstructural Protein NS2 of Bovine Viral Diarrhea Virus Results in Temperature-Sensitive Attenuation of Viral CytopathogenicityPhase 1 Trial of the Dengue Virus Type 4 Vaccine Candidate rDEN4 30-4995 in Healthy Adult VolunteersMicroevolution and virulence of dengue virusesThe neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome.Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from northern Kenya.Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5.Efficacy of a tetravalent chimeric dengue vaccine (DENVax) in Cynomolgus macaquesReplacement of the 3' untranslated variable region of mosquito-borne dengue virus with that of tick-borne Langat virus does not alter vector specificity.Development and clinical evaluation of multiple investigational monovalent DENV vaccines to identify components for inclusion in a live attenuated tetravalent DENV vaccinePatterns of epistasis in RNA viruses: a review of the evidence from vaccine design.Dengue vaccine: priorities and progress.Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3' genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates.Targeted mutagenesis as a rational approach to dengue virus vaccine development.Orthobunyavirus antibodies among humans in selected parts of the Rift Valley and northeastern Kenya.Replacement of conserved or variable sequences of the mosquito-borne dengue virus 3' UTR with homologous sequences from Modoc virus does not change infectivity for mosquitoesDeveloping a dengue vaccine: progress and future challenges.Flavivirus RNA synthesis in vitroBeyond attachment: Roles of DC-SIGN in dengue virus infection.Comparison of full-length genomics sequences between dengue virus serotype 3, parental strain, and its derivatives, and B-cell epitopes prediction from envelope region.
P2860
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P2860
Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Chemical Mutagenesis of Dengue ...... r Cells and Attenuated in Mice
@nl
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@ast
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@en
type
label
Chemical Mutagenesis of Dengue ...... r Cells and Attenuated in Mice
@nl
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@ast
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@en
prefLabel
Chemical Mutagenesis of Dengue ...... r Cells and Attenuated in Mice
@nl
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@ast
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@en
P2093
P2860
P3181
P1433
P1476
Chemical mutagenesis of dengue ...... cells and attenuated in mice.
@en
P2093
Blaney JE Jr
Firestone CY
Johnson DH
Whitehead SS
P2860
P304
P3181
P356
10.1128/JVI.75.20.9731-9740.2001
P577
2001-10-01T00:00:00Z