Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution - Test2 - elhamkhani - TriplyDB

Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

http://www.wikidata.org/entity/Q27480349

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Molecular targets for flavivirus drug discovery Functional RNA elements in the dengue virus genome The role of viral persistence in flavivirus biology Structure and functionality in flavivirus NS-proteins: perspectives for drug design Conservation and variability of dengue virus proteins: implications for vaccine design The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases Structural proteomics of dengue virus Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing Common and unique features of viral RNA-dependent polymerases Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production Analysis of genotype diversity and evolution of Dengue virus serotype 2 using complete genomes Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase Crystal Structure of the NS3 Protease-Helicase from Dengue Virus A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase Specific genetic markers for detecting subtypes of dengue virus serotype-2 in isolates from the states of Oaxaca and Veracruz, Mexico Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein Genomic Epidemiology of a Dengue Virus Epidemic in Urban Singapore Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure Focus on flaviviruses: current and future drug targets Structural explanation for the role of Mn2+ in the activity of 6 RNA-dependent RNA polymerase Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNA Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus 6 from De Novo Initiation to Elongation Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability and de Novo Initiation Activities RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state The many faces of the flavivirus NS5 protein in antagonism of type I interferon signaling Intrinsically Disordered Side of the Zika Virus Proteome Looking for inhibitors of the dengue virus NS5 RNA-dependent RNA-polymerase using a molecular docking approach Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors

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Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

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2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007年の論文

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2007年論文

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2007年论文

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Crystal Structure of the Dengu ...... in at 1.85-Angstrom Resolution

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Helene Malet

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Marie-Pierre Egloff

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Subhash G Vasudevan

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Thai Leong Yap

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Ting Xu

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Yen-Liang Chen

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P2860

A 5' RNA element promotes dengue virus RNA synthesis on a circular genome

The structure of a protein primer-polymerase complex in the initiation of genome replication.

Dengue and dengue hemorrhagic fever

Flavivirus genome organization, expression, and replication

The dengue viruses

trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells.

Mutational analysis of bovine viral diarrhea virus RNA-dependent RNA polymerase.

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A

Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

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10.1128/JVI.02283-06

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