Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein - Test2 - elhamkhani - TriplyDB

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

http://www.wikidata.org/entity/Q27485318

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A new insight into hepatitis C vaccine development Status of hepatitis C virus vaccination: Recent update Monoclonal antibodies: Principles and applications of immmunodiagnosis and immunotherapy for hepatitis C virus Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design JC polyomavirus (JCV) and monoclonal antibodies: friends or potential foes?A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes The hepatitis C virus glycan shield and evasion of the humoral immune response Neutralizing antibody response to hepatitis C virus A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization Statistical linkage analysis of substitutions in patient-derived sequences of genotype 1a hepatitis C virus nonstructural protein 3 exposes targets for immunogen design A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals.Single strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus.Characterization of the envelope glycoproteins associated with infectious hepatitis C virus A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.Characterization of Anti-HCV Antibodies in IL-10-Treated Patients Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization.Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.Mapping a region of hepatitis C virus E2 that is responsible for escape from neutralizing antibodies and a core CD81-binding region that does not tolerate neutralization escape mutations.Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host Neutralizing antibodies and pathogenesis of hepatitis C virus infection.

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Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

http://www.wikidata.org/entity/Q27485318

description

2008 nî lūn-bûn

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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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Journal of Virology

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Identification of a Broadly Cr ...... e Hepatitis C Virus E2 Protein

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P2093

Alexander W Tarr

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Ania Owsianka

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Arvind H Patel

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Jonathan K Ball

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Mario Perotti

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Massimo Clementi

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Nicasio Mancini

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R Adair

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Roberta A Diotti

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Roberto Burioni

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P2860

Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells.

Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteins.

Diverging Effects of Human Recombinant Anti-Hepatitis C Virus (HCV) Antibody Fragments Derived from a Single Patient on the Infectivity of a Vesicular Stomatitis Virus/HCV Pseudotype

Preclinical Evaluation of Two Neutralizing Human Monoclonal Antibodies against Hepatitis C Virus (HCV): a Potential Treatment To Prevent HCV Reinfection in Liver Transplant Patients

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

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1047-52

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scholarly article

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2833998

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10.1128/JVI.01986-07

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2

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82

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2008-01-01T00:00:00Z

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17989176

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Hepatitis C virus

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2224572

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