The RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA Sensors
about
Type-I interferon response affects an inoculation dose-independent mortality in mice following Japanese encephalitis virus infectionPathogen recognition and inflammatory signaling in innate immune defensesRegulation of hepatic innate immunity by hepatitis C virusProtein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responseMechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virusLong double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFNHepatitis C virus reveals a novel early control in acute immune response.Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase RRecombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cellsImplication of PMLIV in both intrinsic and innate immunity.The ribonucleotide reductase R1 subunits of herpes simplex virus 1 and 2 protect cells against poly(I · C)-induced apoptosisDifferential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells.Hepatitis C virus and antiviral innate immunity: who wins at tug-of-war?Activation and evasion of antiviral innate immunity by hepatitis C virus.Central role of ULK1 in type I interferon signalingAdenosine deaminase acting on RNA 1 (ADAR1) suppresses the induction of interferon by measles virus.Protein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection.PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.RNase L Cleavage Products Promote Switch from Autophagy to Apoptosis by Caspase-Mediated Cleavage of Beclin-1.Protein kinase PKR amplification of interferon β induction occurs through initiation factor eIF-2α-mediated translational controlActivation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death.Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.West Nile virus NS2A protein facilitates virus-induced apoptosis independently of interferon response.Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.Between Scylla and Charybdis: the role of the human immune system in the pathogenesis of hepatitis C.Adenosine deaminase ADAR1 increases gene expression at the translational level by decreasing protein kinase PKR-dependent eIF-2alpha phosphorylation.Cationic liposome-nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA.Functional RIG-I-like receptors control the survival of mesenchymal stem cellsDephosphorylation of eIF2alpha mediated by the gamma134.5 protein of herpes simplex virus 1 facilitates viral neuroinvasionRNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment.Measles virus C protein impairs production of defective copyback double-stranded viral RNA and activation of protein kinase R.The multiple faces of proteinkinase R in antiviral defenseThe influence of viral RNA secondary structure on interactions with innate host cell defences.Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response.Bunyaviruses and the type I interferon system.Regulation of Posttranslational Modifications of HMGB1 During Immune Responses
P2860
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P2860
The RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA Sensors
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@ast
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@en
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@nl
type
label
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@ast
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@en
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@nl
altLabel
The RNA-activated protein kina ...... ted by cytoplasmic RNA sensors
@en
prefLabel
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@ast
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@en
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@nl
P2860
P356
P1476
The RNA-activated Protein Kina ...... ted by Cytoplasmic RNA Sensors
@en
P2093
Charles E Samuel
Christopher S McAllister
P2860
P304
P356
10.1074/JBC.M807888200
P407
P577
2009-01-16T00:00:00Z