The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain
about
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architectureThe structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complexAdaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNAGlycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigenIdentification and characterization of the mouse nuclear export factor (Nxf) family membersMultiple Export Mechanisms for mRNAsRNA Export through the NPC in EukaryotesThe crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor.Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15.Coordination of Hpr1 and Ubiquitin Binding by the UBA Domain of the mRNA Export Factor Mex67The crystal structure of the tumor suppressor protein pp32 (Anp32a): Structural insights into Anp32 family of proteinsNovel protein-protein contacts facilitate mRNA 3'-processing signal recognition by Rna15 and Hrp1Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAPThe role of TREX in gene expression and diseaseNuclear export of messenger RNAU2AF participates in the binding of TAP (NXF1) to mRNAUsing viral species specificity to define a critical protein/RNA interaction surfaceComponents of the DNA methylation system of chromatin control are RNA-binding proteinsMutually exclusive interactions drive handover of mRNA from export adaptors to TAPTransport into and out of the nucleus.Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation.Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors.Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information.An element in the 3' untranslated region of human LINE-1 retrotransposon mRNA binds NXF1(TAP) and can function as a nuclear export element.Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surfaceCharge as a selection criterion for translocation through the nuclear pore complex.A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening.Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling.Nuclear export of mRNA.NXF1/p15 heterodimers are essential for mRNA nuclear export in DrosophilaSmall bristles, the Drosophila ortholog of NXF-1, is essential for mRNA export throughout developmentsmall bristles is required for the morphogenesis of multiple tissues during Drosophila development.Structure-based prediction of RNA-binding domains and RNA-binding sites and application to structural genomics targets.Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thaliana.The yeast nuclear pore complex and transport through itdsRBM1 and a proline-rich domain of RNA helicase A can form a composite binder to recognize a specific dsDNAReconstitution of nuclear protein export in isolated nuclear envelopes.Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.
P2860
Q24290505-A38810EF-FB16-4937-8CB9-789895596300Q24306719-81253A2E-2F0D-4F80-9C1D-F82C58E5BDDBQ24320299-86C5C965-FE62-4972-8E15-62687E02B38CQ24534036-760079D8-6D9F-4173-B288-26D0CAE2CB44Q24811084-9E79A40B-93FA-4A3E-B826-3373D6679C0AQ26783595-484C9E7C-9E18-42F4-9765-70737E6B5971Q26824131-BFC02F0E-4E3B-4BAA-9499-9A2180817F04Q27637917-8967B983-F5D0-4DDF-B985-0B38CCE8DEEBQ27641540-38BFD1AF-AD49-4FDF-AA48-D29ACF627710Q27644689-D1460BE7-B220-4DED-B547-53017862511DQ27645802-15C191FB-FC3E-4CFA-A237-072C11A9143CQ27663047-3A780832-F84A-44AB-A444-8B1A1426F211Q27671598-633744C7-43AE-4CE7-B815-C57557E992D5Q28078160-B976CFF2-0E8F-40AB-BAE1-2330E4876850Q28081155-C654082A-36D4-439F-8EA7-406DF9E8CAF1Q28207777-B4D13225-F9FF-4485-9147-B8F7F9A67E76Q28365327-E06E72DD-3CC5-442C-B15B-DD689F30780BQ28509434-ACC71101-6C34-4D58-A170-30749FC46EE1Q28512678-F6B9BED1-FE49-4724-A7CF-EB370688A8EDQ29615611-E309BAA6-694B-4960-9AED-DF94DF105F05Q30432139-0FC89BF2-2CD0-423A-9B63-5172E92F91C1Q30444757-ACB6E7AB-54DB-4303-BAE5-2CE1490C8C7AQ30446940-6CEC87C5-B19C-479D-8129-3B91FEDDE778Q30689200-255D2551-6D37-46B0-8E6A-F180DD88B4DCQ31052823-D02C076C-4E1C-4F3F-ACE7-8C87EB86CE5FQ33285667-1AEAFB25-8B08-4DAF-8DFA-F5FED83FDFDBQ33565505-2AAA3687-DB08-4732-BC99-DBFFF01C2F75Q34084900-1B1746AD-191C-4658-A673-790280237879Q34106560-7F2B76BB-BA4B-4149-AFA9-497D227CD23EQ34286048-AB283F50-0798-45A1-A0AC-C36BF5958F57Q34364086-77D1B3DD-9ABE-4916-9614-453FC69E3ED1Q34364095-85195B22-E364-420A-9F5F-DA6CBC902715Q34613897-EE17D51A-9558-467E-981A-372354BBAC23Q34865111-ACB324B1-213B-4141-AB1C-3911B2C63836Q35579827-3F6F7821-021E-4CEC-893A-A5FB4571F7A8Q35786853-4A6E9FAB-05EC-4AF7-BB81-5630628BBB43Q35810798-2E099E45-7559-430E-A40C-BFF9B2DCE16AQ36119180-C30E48A9-0F61-46D3-9F26-10D2F8984B41Q36323899-0C5036A3-C237-4CEB-90FC-AF1FA2FE04A8Q36325986-8D0C78D1-FEA4-4A5B-8284-B600B50EB8CA
P2860
The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@ast
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@en
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@nl
type
label
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@ast
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@en
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@nl
prefLabel
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@ast
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@en
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@nl
P2093
P2860
P3181
P356
P1433
P1476
The structure of the mRNA expo ...... l RNP domain and an LRR domain
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/19.21.5587
P407
P577
2000-11-01T00:00:00Z