The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor.
about
Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAPComparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors.Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA.Structure-based prediction of RNA-binding domains and RNA-binding sites and application to structural genomics targets.Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.dsRBM1 and a proline-rich domain of RNA helicase A can form a composite binder to recognize a specific dsDNAFormation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export.Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.Amino acid residue doublet propensity in the protein-RNA interface and its application to RNA interface prediction.Atomic resolution structures in nuclear transportSystematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity.
P2860
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P2860
The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor.
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2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
The crystal structure and muta ...... Tap nuclear mRNA export factor
@nl
The crystal structure and muta ...... ap nuclear mRNA export factor.
@ast
The crystal structure and muta ...... ap nuclear mRNA export factor.
@en
type
label
The crystal structure and muta ...... Tap nuclear mRNA export factor
@nl
The crystal structure and muta ...... ap nuclear mRNA export factor.
@ast
The crystal structure and muta ...... ap nuclear mRNA export factor.
@en
prefLabel
The crystal structure and muta ...... Tap nuclear mRNA export factor
@nl
The crystal structure and muta ...... ap nuclear mRNA export factor.
@ast
The crystal structure and muta ...... ap nuclear mRNA export factor.
@en
P2093
P2860
P356
P1476
The crystal structure and muta ...... ap nuclear mRNA export factor.
@en
P2093
Bryan R Cullen
Glen A Coburn
Yibin Kang
P2860
P304
P356
10.1073/PNAS.042698599
P407
P577
2002-02-01T00:00:00Z