Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III
about
Flux balance analysis of mycolic acid pathway: targets for anti-tubercular drugs1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureusThe Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residueThe 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniaeBacterial lipids: metabolism and membrane homeostasisProbing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substratesStructure of 3-oxoacyl-(acyl-carrier protein) synthase II fromThermus thermophilusHB8Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzymeStructure of FabH and factors affecting the distribution of branched fatty acids inMicrococcus luteusInsights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studiesEmergent Decarboxylase Activity and Attenuation of α/β-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in TomatoPathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosisPhosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesisPurification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasBA new family of type III polyketide synthases in Mycobacterium tuberculosisCrystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediatesPurification, characterization, and identification of novel inhibitors of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureusMicrobial type I fatty acid synthases (FAS): major players in a network of cellular FAS systems.Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity.2,5-dialkylresorcinol biosynthesis in Pseudomonas aurantiaca: novel head-to-head condensation of two fatty acid-derived precursorsRoles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae.The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.Product diversity and regulation of type II fatty acid synthases.Comparative cell wall core biosynthesis in the mycolated pathogens, Mycobacterium tuberculosis and Corynebacterium diphtheriae.Characterization of two seryl-tRNA synthetases in albomycin-producing Streptomyces sp. strain ATCC 700974.Protein targets for structure-based anti-Mycobacterium tuberculosis drug discovery.Fatty acid biosynthesis in actinomycetes.Phloretin Exerts Anti-Tuberculosis Activity and Suppresses Lung Inflammation.AccD6, a key carboxyltransferase essential for mycolic acid synthesis in Mycobacterium tuberculosis, is dispensable in a nonpathogenic strainCoexpression of genetically engineered 3-ketoacyl-ACP synthase III (fabH) and polyhydroxyalkanoate synthase (phaC) genes leads to short-chain-length-medium-chain-length polyhydroxyalkanoate copolymer production from glucose in Escherichia coli JM109Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability.The C- and N-Terminal Residues of Synthetic Heptapeptide Ion Channels Influence Transport Efficacy Through Phospholipid Bilayers.A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites.Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
P2860
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P2860
Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structure of the Mycob ...... l carrier protein synthase III
@ast
Crystal structure of the Mycob ...... l carrier protein synthase III
@en
Crystal structure of the Mycob ...... l carrier protein synthase III
@nl
type
label
Crystal structure of the Mycob ...... l carrier protein synthase III
@ast
Crystal structure of the Mycob ...... l carrier protein synthase III
@en
Crystal structure of the Mycob ...... l carrier protein synthase III
@nl
prefLabel
Crystal structure of the Mycob ...... l carrier protein synthase III
@ast
Crystal structure of the Mycob ...... l carrier protein synthase III
@en
Crystal structure of the Mycob ...... l carrier protein synthase III
@nl
P2093
P2860
P921
P356
P1476
Crystal structure of the Mycob ...... l carrier protein synthase III
@en
P2093
G Kazanina
H T Wright
J N Scarsdale
K A Reynolds
P2860
P304
P356
10.1074/JBC.M010762200
P407
P577
2001-06-08T00:00:00Z