A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites.
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Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandiiExploiting the Biosynthetic Potential of Type III Polyketide SynthasesDistinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassaA structure-based mechanism for benzalacetone synthase from Rheum palmatumStructural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativaBiochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13Crystal Structure of Mycobacterium tuberculosis Polyketide Synthase 11 (PKS11) Reveals Intermediates in the Synthesis of Methyl-branched AlkylpyronesStructure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer BiosynthesisStructural Basis for Cyclization Specificity of Two Azotobacter Type III Polyketide Synthases: A SINGLE AMINO ACID SUBSTITUTION REVERSES THEIR CYCLIZATION SPECIFICITYPapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1Structure-function relationships in plant phenylpropanoid biosynthesisA polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones.Molecular cloning, modeling, and site-directed mutagenesis of type III polyketide synthase from Sargassum binderi (Phaeophyta).Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.Allergens/Antigens, toxins and polyketides of important Aspergillus species.Crystallization and preliminary X-ray crystallographic studies of the N-terminal domain of FadD28, a fatty-acyl AMP ligase from Mycobacterium tuberculosis.Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2'-oxoalkylresorcinol synthase.Crystallization and preliminary crystallographic analysis of an acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata.Phylogenetic and Structural Analysis of Polyketide Synthases in Aspergilli.Heterologous expression systems for polyketide synthases.Biosynthesis of mycobacterial lipids by polyketide synthases and beyond.Fascinating potential of aspergilli.Structural basis for the formation of acylalkylpyrones from two β-ketoacyl units by the fungal type III polyketide synthase CsyB.Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilisLAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.Chain elongation and cyclization in type III PKS DpgA.Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases.Dissecting the functional role of polyketide synthases in Dictyostelium discoideum: biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol.Hypericum perforatum hydroxyalkylpyrone synthase involved in sporopollenin biosynthesis--phylogeny, site-directed mutagenesis, and expression in nonanther tissues.Characterization of the substrate specificity of PhlD, a type III polyketide synthase from Pseudomonas fluorescens.Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum.Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase.
P2860
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P2860
A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@en
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@nl
type
label
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@en
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@nl
prefLabel
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@en
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@nl
P2093
P2860
P356
P1476
A novel tunnel in mycobacteria ...... enerating diverse metabolites.
@en
P2093
Priti Saxena
Rajan Sankaranarayanan
Rajesh S Gokhale
Raju Rukmini
Uttara B Marathe
Vellaiah M Shanmugam
P2860
P2888
P304
P356
10.1038/NSMB809
P577
2004-08-01T00:00:00Z
P6179
1034611491