Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2
about
Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradationA glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised.The orthology of HLA-E and H2-Qa1 is hidden by their concerted evolution with other MHC class I molecules.Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentationStructure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptorCrystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulationStructural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1 reveals a paradigm for MHC/MHC interaction in immune evasionStructural Mechanism of ER Retrieval of MHC Class I by CowpoxDissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatinERAD: the long road to destructionSignal peptide-dependent inhibition of MHC class I heavy chain translation by rhesus cytomegalovirusT-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APCRequirements for the selective degradation of endoplasmic reticulum-resident major histocompatibility complex class I proteins by the viral immune evasion molecule mK3.Rhesus cytomegalovirus contains functional homologues of US2, US3, US6, and US11.T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.A role for N-glycanase in the cytosolic turnover of glycoproteins.The MHC class I antigen presentation pathway: strategies for viral immune evasion.The human cytomegalovirus US8 glycoprotein binds to major histocompatibility complex class I products.Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.Lessons from viral manipulation of protein disposal pathwaysBinding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation.How the virus outsmarts the host: function and structure of cytomegalovirus MHC-I-like molecules in the evasion of natural killer cell surveillanceThe cytoplasmic domain of rhesus cytomegalovirus Rh178 interrupts translation of major histocompatibility class I leader peptide-containing proteins prior to translocation.Human cytomegalovirus US2 causes similar effects on both major histocompatibility complex class I and II proteins in epithelial and glial cellsImmune interactions at the maternal-fetal interface: a focus on antigen presentation.Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules.Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayerViral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond.Viral strategies for evading antiviral cellular immune responses of the host.Herpesvirus interference with major histocompatibility complex class II-restricted T-cell activation.A bipartite trigger for dislocation directs the proteasomal degradation of an endoplasmic reticulum membrane glycoproteinEndoplasmic reticulum chaperones participate in human cytomegalovirus US2-mediated degradation of class I major histocompatibility complex molecules.Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway.Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1(CCMV)Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity.Diverse immune evasion strategies by human cytomegalovirus.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.Classical and non-classical MHC I molecule manipulation by human cytomegalovirus: so many targets—but how many arrows in the quiver?Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein.Physical association of the K3 protein of gamma-2 herpesvirus 68 with major histocompatibility complex class I molecules with impaired peptide and beta(2)-microglobulin assembly.
P2860
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P2860
Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Antigen presentation subverted ...... to the class I molecule HLA-A2
@ast
Antigen presentation subverted ...... to the class I molecule HLA-A2
@en
Antigen presentation subverted ...... to the class I molecule HLA-A2
@nl
type
label
Antigen presentation subverted ...... to the class I molecule HLA-A2
@ast
Antigen presentation subverted ...... to the class I molecule HLA-A2
@en
Antigen presentation subverted ...... to the class I molecule HLA-A2
@nl
prefLabel
Antigen presentation subverted ...... to the class I molecule HLA-A2
@ast
Antigen presentation subverted ...... to the class I molecule HLA-A2
@en
Antigen presentation subverted ...... to the class I molecule HLA-A2
@nl
P2093
P2860
P356
P1476
Antigen presentation subverted ...... to the class I molecule HLA-A2
@en
P2093
P2860
P304
P356
10.1073/PNAS.121172898
P407
P577
2001-06-05T00:00:00Z