Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis
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ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndromeCharacterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug developmentStructure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniaeCrystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesisStructure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathwayStructure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development.Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinaseSynthesis of CDP-Activated Ribitol for Teichoic Acid Precursors in Streptococcus pneumoniaeStructural and functional studies of mycobacterial IspD enzymesExperimental and computational active site mapping as a starting point to fragment-based lead discoveryPseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspDNew Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in PlasmodiumIsoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasitesFrancisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulationFractal Dimensions of Macromolecular Structures.The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan additionExpression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.Lethal mutations in the isoprenoid pathway of Salmonella entericaTerpene Specialized Metabolism in Arabidopsis thalianaThe plastid-derived organelle of protozoan human parasites as a target of established and emerging drugs.Identification of mutations in TMEM5 and ISPD as a cause of severe cobblestone lissencephalyPlasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.Targeting the formation of the cell wall core of M. tuberculosis.The non-mevalonate pathway of isoprenoid precursor biosynthesis.The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspDMechanistic aspects of carotenoid biosynthesis.Convergent strategies in biosynthesis.Biochemistry of the non-mevalonate isoprenoid pathway.Methylerythritol 4-phosphate (MEP) pathway metabolic regulation.Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using (1)H-(31)P-(31)P correlation NMR spectroscopy.Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE.A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis.Resurrecting the ancestral enzymatic role of a modulatory subunit.Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.The MEP pathway and the development of inhibitors as potential anti-infective agentsIdentification and Characterization of Bioactive Compounds Targeting UropathogenicEscherichia colifrom Sanjin Tablets
P2860
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P2860
Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@ast
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@en
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@nl
type
label
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@ast
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@en
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@nl
prefLabel
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@ast
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@en
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@nl
P2093
P3181
P356
P1476
Structure of 4-diphosphocytidy ...... endent isoprenoid biosynthesis
@en
P2093
M E Bowman
S B Richard
W Kwiatkowski
P3181
P356
10.1038/89691
P407
P577
2001-07-01T00:00:00Z