Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase
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Global phenotypic screening for antimalarialsThe potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoidsStudies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agentsX-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacyType I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structureDesign and Synthesis of Aryl Ether Inhibitors of theBacillus AnthracisEnoyl-ACP ReductaseThe Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial ParasitesTriclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosisSlow-Onset Inhibition of the FabI Enoyl Reductase from Francisella tularensis : Residence Time and in Vivo ActivityIdentification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl ReductaseEffect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparumHigh-resolution structures ofThermus thermophilusenoyl-acyl carrier protein reductase in the apo form, in complex with NAD+and in complex with NAD+and triclosanThe benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme targetThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsThe mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acidMechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia malleiDynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery.Delivery of antimicrobials into parasitesAn update on the rapid advances in malaria parasite cell biology.Targeting the Lipid Metabolic Pathways for the Treatment of Malaria.Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum.In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitorsPotential impact of increased use of biocides in consumer products on prevalence of antibiotic resistanceEnzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex.Antimalarial drug discovery: efficacy models for compound screening.Parasite plastids: approaching the endgame.The plastid-derived organelle of protozoan human parasites as a target of established and emerging drugs.Virtually Designed Triclosan-Based Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis and of Plasmodium falciparum.Make it or take it: fatty acid metabolism of apicomplexan parasitesNew advances in fatty acids as antimalarial, antimycobacterial and antifungal agents.Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase.Plasmodium falciparum apicoplast transit peptides are unstructured in vitro and during apicoplast import.Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agentsSynthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.The (5Z)-5-Pentacosenoic and 5-Pentacosynoic Acids Inhibit the HIV-1 Reverse Transcriptase.Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansDiscrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis.
P2860
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P1343
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P2860
Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
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2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Structural elucidation of the ...... acyl carrier protein reductase
@ast
Structural elucidation of the ...... acyl carrier protein reductase
@en
Structural elucidation of the ...... acyl carrier protein reductase
@nl
type
label
Structural elucidation of the ...... acyl carrier protein reductase
@ast
Structural elucidation of the ...... acyl carrier protein reductase
@en
Structural elucidation of the ...... acyl carrier protein reductase
@nl
prefLabel
Structural elucidation of the ...... acyl carrier protein reductase
@ast
Structural elucidation of the ...... acyl carrier protein reductase
@en
Structural elucidation of the ...... acyl carrier protein reductase
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P2093
P2860
P921
P356
P1476
Structural elucidation of the ...... acyl carrier protein reductase
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P2093
Amar bir Singh Sidhu
Jacob T Valiyaveettil
James C Sacchettini
Remo Perozzo
Robert Bittman
P2860
P304
13106-13114
P356
10.1074/JBC.M112000200
P407
P577
2002-01-15T00:00:00Z