Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b
about
ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motifCrystal structure of the p38 alpha-MAPKAP kinase 2 heterodimerA distinct interaction mode revealed by the crystal structure of the kinase p38α with the MAPK binding domain of the phosphatase MKP5Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinasesBidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPKActivation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase.Structural mechanism for the specific assembly and activation of the extracellular signal regulated kinase 5 (ERK5) moduleSpecificity of linear motifs that bind to a common mitogen-activated protein kinase docking grooveSubstrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifsSelectivity of docking sites in MAPK kinasesRegulation of PRAK subcellular location by p38 MAP kinasesp38 MAPK in cardioprotection - are we there yet?MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPKRecognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domainMolecular basis of MAPK-activated protein kinase 2:p38 assemblyStructural and Functional Characterization of the Human Protein Kinase ASK1The Structure of the MAP2K MEK6 Reveals an Autoinhibitory DimerKinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein PhosphorylationStructural Mechanisms of Allostery and Autoinhibition in JNK Family KinasesProtein–peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinaseX-ray structure of p38α bound to TAK-715: comparison with three classic inhibitorsCrystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1Domain-Swapping Switch Point in Ste20 Protein Kinase SPAKERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1Differential regulation and properties of MAPKsSubdomain VIII is a specificity-determining region in MEKK1Structural and functional divergence of two fish aquaporin-1 water channels following teleost-specific gene duplicationERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsGlyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death.The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1.Interface analysis of the complex between ERK2 and PTP-SLIonizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.Substrate and docking interactions in serine/threonine protein kinasesA simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs.A model of a MAPK•substrate complex in an active conformation: a computational and experimental approachExpanding the repertoire of an ERK2 recruitment site: cysteine footprinting identifies the D-recruitment site as a mediator of Ets-1 binding.Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446.Three-dimensional docking in the MAPK p38α.
P2860
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P2860
Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@ast
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@en
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@nl
type
label
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@ast
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@en
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@nl
prefLabel
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@ast
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@en
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@nl
P2093
P3181
P1433
P1476
Crystal structures of MAP kina ...... rate MEF2A and activator MKK3b
@en
P2093
Chung I Chang
Elizabeth J Goldsmith
Radha Akella
P304
P3181
P356
10.1016/S1097-2765(02)00525-7
P577
2002-06-01T00:00:00Z