The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates

The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates

Item
http://www.wikidata.org/entity/Q27639354
Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cellsCrystal structure of PTP1B complexed with a potent and selective bidentate inhibitorStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionNitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition stateA two stage click-based library of protein tyrosine phosphatase inhibitorsPhosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.Recent advances in protein tyrosine phosphatase 1B inhibitors.Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase.Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice.Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.
P2860

The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates

Item
http://www.wikidata.org/entity/Q27639354
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@ast
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@en
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@nl
type
label
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@ast
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@en
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@nl
prefLabel
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@ast
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@en
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
The structure of PTP-1B in com ...... nding mode for bisphosphonates
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698