Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition - Test2 - elhamkhani - TriplyDB

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

http://www.wikidata.org/entity/Q27639443

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Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production G protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1 Recognition and accommodation at the androgen receptor coactivator binding interface Functions of the Hsp90 chaperone system: lifting client proteins to new heights The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism Structural plasticity in the oestrogen receptor ligand-binding domain Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazol Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor Mechanisms for the Evolution of a Derived Function in the Ancestral Glucocorticoid Receptor Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors Structures and mechanism for the design of highly potent glucocorticoids GEN3VA: aggregation and analysis of gene expression signatures from related studies Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta action 3D model of lamprey estrogen receptor with estradiol and 15alpha-hydroxy-estradiol Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy Structure of a 13-fold superhelix (almost) determined from first principles.Ultrafast protein structure-based virtual screening with Panther.Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics.Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors.Investigation on critical structural motifs of ligands for triggering glucocorticoid receptor nuclear migration through molecular docking simulations.Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled.The human glucocorticoid receptor: molecular basis of biologic function The helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones.A new strategy for selective targeting of progesterone receptor with passive antagonists.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases Minireview: latest perspectives on antiinflammatory actions of glucocorticoids.Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor.

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

http://www.wikidata.org/entity/Q27639443

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2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Crystal structure of the gluco ...... on and coactivator recognition

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Christopher J Apolito

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David D McKee

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Derek J Parks

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Eugene L Stewart

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H Eric Xu

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John T Moore

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Millard H Lambert

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10.1016/S0092-8674(02)00817-6

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