BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityPurified human BRCA2 stimulates RAD51-mediated recombinationCDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repairBRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damageBRCA2 suppresses cell proliferation via stabilizing MAGE-D1Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeatsHSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage responsePALB2 regulates recombinational repair through chromatin association and oligomerizationThe BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiaeRec2 interplay with both Brh2 and Rad51 balances recombinational repair in Ustilago maydisThe BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repairFunctional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatinHomologous recombination in DNA repair and DNA damage toleranceInteractions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantumSusceptibility pathways in Fanconi's anemia and breast cancerHow the fanconi anemia pathway guards the genomeThe process of displacing the single-stranded DNA-binding protein from single-stranded DNA by RecO and RecR proteinsTrypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombinationA multiprotein nuclear complex connects Fanconi anemia and Bloom syndromeNew insights into the biological function of BRCA2 from its structural interactionsDissecting systems-wide data using mixture models: application to identify affected cellular processes.From systems to structure: bridging networks and mechanismGenetic variations in colorectal cancer risk and clinical outcomeSingle-stranded DNA-binding proteins: multiple domains for multiple functionsRoles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafishDeep trefoil knot implicated in RNA binding found in an archaebacterial proteinInsights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB proteinNucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexesFull-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2Recognition of DNA substrates by T4 bacteriophage polynucleotide kinaseStructure of a Virulence Regulatory Factor CvfB Reveals a Novel Winged Helix RNA Binding ModuleStructures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodiesStructural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NCMechanism of RecO recruitment to DNA by single-stranded DNA binding proteinStructure-function analysis of pneumococcal DprA protein reveals that dimerization is crucial for loading RecA recombinase onto DNA during transformationMolecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome ActivationA genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicingThe 26S proteasome drives trinucleotide repeat expansionsRoles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing
P2860
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P2860
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@ast
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@en
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@nl
type
label
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@ast
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@en
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@nl
prefLabel
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@ast
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@en
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@nl
P2093
P3181
P1433
P1476
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
@en
P2093
Elspeth Kinnucan
Haijuan Yang
Julie Miller
Nicolas H Thoma
Nikola P Pavletich
Ning Zheng
Phang-Lang Chen
Philip D Jeffrey
Wen-Hwa Lee
Yutong Sun
P304
P3181
P356
10.1126/SCIENCE.297.5588.1837
P407
P577
2002-09-13T00:00:00Z