Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
about
Cyclotide structure-activity relationships: qualitative and quantitative approaches linking cytotoxic and anthelmintic activity to the clustering of physicochemical forcesA continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae)Trp-26 imparts functional versatility to human alpha-defensin HNP1Hepcidin revisited, disulfide connectivity, dynamics, and structureEvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environmentsSolution NMR studies on the orientation of membrane-bound peptides and proteins by paramagnetic probesCombined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug ScaffoldDespite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding ModesDesign, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACINGThe α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistanceSemienzymatic Cyclization of Disulfide-rich Peptides Using Sortase ASolution structure of the circular γ-domain analog from the wheat metallothionein E(c)-1Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffoldsAntimicrobial Peptides from PlantsComputational Design of Hypothetical New Peptides Based on a Cyclotide Scaffold as HIV gp120 InhibitorNatural products in modern life science.NMR and protein structure in drug design: application to cyclotides and conotoxins.Tyrosine-rich conopeptides affect voltage-gated K+ channels.Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.Disulfide mapping of the cyclotide kalata B1. Chemical proof of the cystic cystine knot motif.Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.Knottin cyclization: impact on structure and dynamics.Mechanical strength of 17,134 model proteins and cysteine slipknotsLigand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptorsMacrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin.Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activityMolecular dynamics exploration of poration and leaking caused by Kalata B1 in HIV-infected cell membrane compared to host and HIV membranesCytotoxic potency of small macrocyclic knot proteins: structure-activity and mechanistic studies of native and chemically modified cyclotides.Protease-resistant peptide ligands from a knottin scaffold library.Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator.The chemistry and biology of theta defensins.Dynamic scenario of membrane binding process of kalata b1Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric poresIdentification and structural characterization of novel cyclotide with activity against an insect pest of sugar caneHost-defense activities of cyclotides.Biological activities of natural and engineered cyclotides, a novel molecular scaffold for peptide-based therapeutics.
P2860
Q21132291-DDAAF27D-9679-4D94-B34A-8CA200E5B6E6Q24536656-9ECDCB7A-C304-4509-8A64-62A0FDB9ACE6Q24615312-607BCD8B-64D5-4788-A35F-12551E2EE594Q24651444-99B03B0A-C5D6-4305-80D1-7D0D4F102DD9Q24792678-F898E593-12E7-4498-B3E4-C00CB5278070Q27024724-00075806-BBA3-4D7F-9B47-D6FE148F1590Q27653739-57CDDA57-474F-401F-884B-79681C77DEA0Q27657245-D8D5B310-10AE-4271-8DC0-5B96488605EEQ27673637-85B39C08-9037-4EAB-8D71-0DC751C345B2Q27676696-AC36EDFE-D06D-41F3-B2ED-4A676EAFAAD4Q27676939-83C1FCEE-242D-494C-A5C4-7BC616D8C163Q27681346-026895A3-3421-4CB8-BC53-77EAAE96A646Q27687708-E33B0C54-44CD-424E-9DDB-5A050FE7693CQ27694819-E44E563C-E643-455D-95C1-4B8125BFFCFFQ28082004-F9E9285C-B942-407F-A9DB-59E8F1FCFD3CQ28550563-090CA2B1-8468-4572-B9B5-8C1AB133D2BAQ28750059-523B3696-F0E3-4827-AE64-4D1698ABF3A0Q30399297-05073485-40B7-49F8-B151-29BD0DCB6FB2Q30487419-2765FA3E-8A18-473D-8393-1CE386834438Q30916250-AA290CF6-C045-476C-8538-570420F9F07AQ31156133-BEB53601-E268-4CBF-8114-2234467B4ED3Q33205507-F54ECBD1-B38F-4D03-85CE-B27F76B9D4E5Q33251958-DEB20BCC-E814-4357-B439-03C8AF37C0C4Q33392477-D16E3358-FBC0-49EC-A533-FE36834C5FE1Q33513957-71230B12-7103-41B4-B785-B152C6A81EADQ33650270-BE9ADED7-A1A0-447C-8698-54AC1489A887Q33795132-7386C28C-2FA6-47F6-8B9C-97AF28C751BDQ33796227-DFEFF98F-9BF8-4F4D-946F-4E665718BAF8Q33804191-B7341978-409E-4A39-8F56-3E8539336F44Q33872337-8522487A-D698-403F-9118-C78A4D4C6ABFQ33912692-863D69C1-6DF0-45A8-87D8-F9377CA7EFB8Q34048086-96B07D9D-C4B2-4D58-86EA-C73EB2860260Q34321700-2DFD62FA-B565-4B64-8DCB-440E4AFAB350Q34431648-468225EA-6CFE-4A16-9A33-CED666F0979AQ34634734-211FBD36-78FF-43AF-B9DC-33E35804213CQ34747442-26F70E33-63F6-4AF3-B226-51EE340D9FF1Q34984555-CF8E06AA-E0D9-42E4-A6BA-017D70A75A1DQ35643590-937D2FAF-42B0-4AC0-B5B7-009D1E04FB04Q35864573-DC6707B7-1604-4FAF-B6EB-8E8672E3573CQ35893500-4CF402C7-BF70-4304-BB67-BEC99F86F37E
P2860
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@ast
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@en
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@nl
type
label
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@ast
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@en
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@nl
prefLabel
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@ast
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@en
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@nl
P2860
P50
P356
P1476
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework
@en
P2093
Clement Waine
Manuel R Plan
P2860
P304
P356
10.1074/JBC.M211147200
P407
P577
2002-12-12T00:00:00Z