Crystal structure of the catalytic domain of the PknB serine/threonine kinase from Mycobacterium tuberculosis
about
Structural evolution of the protein kinase-like superfamilyDiversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotesStructural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis.Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA SplicingAuto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinaseAllosteric Activation Mechanism of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknBAminoglycoside 2′′-Phosphotransferase IIIa (APH(2′′)-IIIa) Prefers GTP over ATPStructural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknBStructure of the Sensor Domain of Mycobacterium tuberculosis PknH Receptor Kinase Reveals a Conserved Binding CleftThe crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformationEvidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosisAllosteric activation by dimerization of the PknD receptor Ser/Thr protein kinase from Mycobacterium tuberculosisAn ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in miceThe Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape.The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growthMycobacterium tuberculosis protein kinase K enables growth adaptation through translation controlValidated LC--MS/MS method for determination of YH-8, a novel PKnB inhibitor, in rat plasma and its application to pharmacokinetic studyEnhanced ranking of PknB Inhibitors using data fusion methods.A framework for classification of prokaryotic protein kinasesProtein kinase B (PknB) of Mycobacterium tuberculosis is essential for growth of the pathogen in vitro as well as for survival within the host.Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains.Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinasesEffective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents.A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activityThe extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localizationCharacterization of a eukaryotic-like tyrosine protein kinase expressed by the Shiga toxin-encoding bacteriophage 933WSer/Thr/Tyr protein phosphorylation in bacteria - for long time neglected, now well established.Mycobacterium tuberculosis Serine/Threonine Protein Kinases.Bacterial growth and cell division: a mycobacterial perspective.Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S centerReciprocal regulation of cephalosporin resistance in Enterococcus faecalis.Aspects of eukaryotic-like signaling in Gram-positive cocci: a focus on virulence.Identification and classification of small molecule kinases: insights into substrate recognition and specificity.Structure/function studies of Ser/Thr and Tyr protein phosphorylation in Mycobacterium tuberculosis.Evolutionary Ancestry of Eukaryotic Protein Kinases and Choline KinasesActivation of PKR: an open and shut case?Key residues in Mycobacterium tuberculosis protein kinase G play a role in regulating kinase activity and survival in the host.Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases.Eukaryote-like serine/threonine kinases and phosphatases in bacteria.Bacterial cell division regulation by Ser/Thr kinases: a structural perspective
P2860
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P2860
Crystal structure of the catalytic domain of the PknB serine/threonine kinase from Mycobacterium tuberculosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@ast
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@en
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@nl
type
label
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@ast
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@en
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@nl
prefLabel
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@ast
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@en
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@nl
P2093
P2860
P356
P1476
Crystal structure of the catal ...... rom Mycobacterium tuberculosis
@en
P2093
Brigitte Boitel
Frédérique Pompeo
Miguel Ortiz-Lombardía
P2860
P304
P356
10.1074/JBC.M300660200
P407
P577
2003-04-11T00:00:00Z