Protein kinase B (PknB) of Mycobacterium tuberculosis is essential for growth of the pathogen in vitro as well as for survival within the host.
about
Identification of Ser/Thr kinase and forkhead associated domains in Mycobacterium ulcerans: characterization of novel association between protein kinase Q and MupFHAStructural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding SiteA novel STK1-targeted small-molecule as an "antibiotic resistance breaker" against multidrug-resistant Staphylococcus aureus.A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activityComparative Ser/Thr/Tyr phosphoproteomics between two mycobacterial species: the fast growing Mycobacterium smegmatis and the slow growing Mycobacterium bovis BCG.Protein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host.The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 bindingDepletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and VirulenceThe external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growthRv2744c Is a PspA Ortholog That Regulates Lipid Droplet Homeostasis and Nonreplicating Persistence in Mycobacterium tuberculosis.Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system.Regulation of transcription by eukaryotic-like serine-threonine kinases and phosphatases in Gram-positive bacterial pathogens.A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA.Distribution of PASTA domains in penicillin-binding proteins and serine/threonine kinases of Actinobacteria.Insight into the structural requirements of aminopyrimidine derivatives for good potency against both purified enzyme and whole cells of M. tuberculosis: combination of HQSAR, CoMSIA, and MD simulation studies.The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.Key Structures and Interactions for Binding of Mycobacterium tuberculosis Protein Kinase B Inhibitors from Molecular Dynamics Simulation.Serine/Threonine Protein Phosphatase PstP of Mycobacterium tuberculosis Is Necessary for Accurate Cell Division and Survival of Pathogen.Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.Do Shoot the Messenger: PASTA Kinases as Virulence Determinants and Antibiotic Targets.Protein Kinase G confers survival advantage to Mycobacterium tuberculosis during latency like conditions.Growth- and stress-induced PASTA kinase phosphorylation in Enterococcus faecalis.PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis.Inhibition of the DevSR Two-Component System by Overexpression of Mycobacterium tuberculosis PknB in Mycobacterium smegmatis.PASTA repeats of the protein kinase StkP interconnect cell constriction and separation of Streptococcus pneumoniae.Drug targets in dormant Mycobacterium tuberculosis: can the conquest against tuberculosis become a reality?Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation.Lauric acid and myristic acid from Allium sativum inhibit the growth of Mycobacterium tuberculosis H37Ra: in silico analysis reveals possible binding to protein kinase B.The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.Structural and dynamic features of PASTA domains with different functional roles.Delineating FtsQ-mediated regulation of cell division in
P2860
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P2860
Protein kinase B (PknB) of Mycobacterium tuberculosis is essential for growth of the pathogen in vitro as well as for survival within the host.
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Protein kinase B (PknB) of Myc ...... for survival within the host.
@ast
Protein kinase B (PknB) of Myc ...... for survival within the host.
@en
type
label
Protein kinase B (PknB) of Myc ...... for survival within the host.
@ast
Protein kinase B (PknB) of Myc ...... for survival within the host.
@en
prefLabel
Protein kinase B (PknB) of Myc ...... for survival within the host.
@ast
Protein kinase B (PknB) of Myc ...... for survival within the host.
@en
P2093
P2860
P356
P1476
Protein kinase B (PknB) of Myc ...... for survival within the host.
@en
P2093
Francesca Forti
Sandeep Upadhyay
Sathya Narayanan Nagarajan
Shazia Khan
P2860
P304
13858-13875
P356
10.1074/JBC.M114.563536
P407
P577
2014-04-04T00:00:00Z