about
The Vpr protein from HIV-1: distinct roles along the viral life cycleThe mitochondriotoxic domain of Vpr determines HIV-1 virulenceLentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycleFormation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrestNMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micellesStructural basis of lentiviral subversion of a cellular protein degradation pathwayThe DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destructionAnti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastomaCharacterization of a novel type of HIV-1 particle assembly inhibitor using a quantitative luciferase-Vpr packaging-based assayNuclear exportin receptor CAS regulates the NPI-1-mediated nuclear import of HIV-1 VprSynthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 InhibitorThe inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain.Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions.HIV-1 Vpr oligomerization but not that of Gag directs the interaction between Vpr and Gag.Peptide HIV-1 integrase inhibitors from HIV-1 gene products.Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding.Vpr-host interactions during HIV-1 viral life cycle.Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of VPR.Exposed hydrophobic residues in human immunodeficiency virus type 1 Vpr helix-1 are important for cell cycle arrest and cell deathHIV-1 Vpr redirects host ubiquitination pathway.The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domainsHIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction.Peptides that inhibit HIV-1 integrase by blocking its protein-protein interactions.Nuclear magnetic resonance structure revealed that the human polyomavirus JC virus agnoprotein contains an α-helix encompassing the Leu/Ile/Phe-rich domain.Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.Development of a robust cell-based high-throughput screening assay to identify targets of HIV-1 viral protein R dimerization.HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionEffect on HIV-1 gene expression, Tat-Vpr interaction and cell apoptosis by natural variants of HIV-1 Tat exon 1 and Vpr from Northern IndiaDeterminants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.Solution structure of kurtoxin: a gating modifier selective for Cav3 voltage-gated Ca(2+) channelsVpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cellsLocalization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophagesA protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complexA comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopesHuman immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.Human immunodeficiency virus viral protein R as an extracellular protein in neuropathogenesis.
P2860
Q21245211-6EC087FB-C4FB-4A1A-924F-8620701B7C5BQ24674929-C6ADB393-9E5B-4D2D-870D-7C2C39000619Q24680705-35B74E6C-A056-400F-ADEE-88CFA446103DQ27313676-D9C616CF-7538-4060-948D-DD2334AD3438Q27657668-9A4669D1-8BE1-4168-A4D8-E6E4C8F21D7DQ27680878-C3F47709-BE8C-4A38-ACFE-18271E8FD715Q27727807-2EB6C616-2CF3-494E-A261-B22BE92D91F5Q28474789-F7F20242-FB06-496E-964E-C6D65CC1B0E1Q28477791-F89EE950-813D-4599-ABD6-2528DDE27E07Q28478027-7F4EE645-F557-48A9-8587-C896F173EB4FQ28551700-758E7EBB-8770-418E-B28D-0FB96BE4E6A9Q30440445-AE0E7271-7E6F-4362-BA81-45FD6B99BDC7Q33511235-BF7396B6-CD36-42BB-9BB6-BBA178789AAEQ33614489-8E17B9AB-A031-4C12-B3D6-F6BBB2D4ADCAQ33619612-3ECD91DF-FA64-4D49-AFC3-FA66B05A58DEQ33657660-5D34711C-EBDB-42E2-AAF6-C6D86CCFBA2BQ33710135-D3C1F5EA-B315-4729-969E-9E142011BD0EQ33828332-4F2AB8CA-B054-48E6-B226-A5216B263CB6Q33831542-97C19B60-7670-4C5C-9643-F5627DC91B13Q34031619-419F93B5-F71F-4688-8629-8B6B69BC5A5CQ34059218-90BEE754-9EB8-49D9-BEC9-9E687F01A637Q34106660-E7DF6422-8804-4FE3-9C23-FF1506B7CB58Q34206410-777824E4-A8F6-4792-ADDE-E239CCC4EBA0Q34320018-E98DBAC0-903F-4798-9345-10DDC1321F27Q34412296-66BC609F-4296-4754-AFBD-6F0FFEE7CEB8Q34554287-0E01B94C-001D-45E9-A5B5-E33B8E462B17Q34758051-5E0129D4-8EDF-4597-84DA-9520747B53FAQ34957142-657CED70-8A45-402C-A628-216108CF0B13Q35075250-2C104DA4-E014-46F1-8C25-450B07A8E610Q35684278-31AB9F52-6205-4BB9-A018-24A142950611Q35807764-0BC4A414-FEBF-4C6F-875F-EA6A954C3C26Q35948038-327D6625-AC01-4B23-9589-9604AB6C9E15Q36398981-49BAF0CA-D0D2-4E2A-9313-56BA5EA175DBQ36553297-6701E067-A989-4A23-8362-2674E75334D1Q36890536-BCEC1B9A-18EE-46DA-BCF5-2398CC65F8D7Q36908259-8D215AEA-4177-430E-8ED5-82EB65569BA9Q36940407-77A1F580-B7FE-4D35-A0C1-97D12CFCE20BQ36994727-EAF31B03-CB0C-4E40-B0B7-5CDA4329BC26Q37029922-ADFF12E9-D282-49A0-9401-E35A98E6E87CQ37063467-DD7BF144-D2EF-453B-8F70-D8FE50FA9CC4
P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
NMR structure of the HIV-1 regulatory protein VPR
@ast
NMR structure of the HIV-1 regulatory protein VPR
@en
NMR structure of the HIV-1 regulatory protein VPR
@nl
type
label
NMR structure of the HIV-1 regulatory protein VPR
@ast
NMR structure of the HIV-1 regulatory protein VPR
@en
NMR structure of the HIV-1 regulatory protein VPR
@nl
prefLabel
NMR structure of the HIV-1 regulatory protein VPR
@ast
NMR structure of the HIV-1 regulatory protein VPR
@en
NMR structure of the HIV-1 regulatory protein VPR
@nl
P2093
P3181
P1476
NMR structure of the HIV-1 regulatory protein VPR
@en
P2093
B P Roques
P Petitjean
P304
P3181
P356
10.1016/S0022-2836(03)00060-3
P407
P577
2003-03-01T00:00:00Z