Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.
about
Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infectionHIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage responseHIV-1 Vpr and G2 cell cycle arrest.Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells.Human immunodeficiency virus type 1 Vif causes dysfunction of Cdk1 and CyclinB1: implications for cell cycle arrest.Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest.Changing the ubiquitin landscape during viral manipulation of the DNA damage response.HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.The human immunodeficiency virus type 1 Vpr protein and its carboxy-terminally truncated form induce apoptosis in tumor cells.HIV-1 Vpr-a still "enigmatic multitasker".Roles of Vpr and Vpx in modulating the virus-host cell relationship.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.Restricted access to myeloid cells explained.Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase.Cell context-dependent involvement of ATR in early stages of retroviral replicationFrom arrest to escape: HIV-1 Vpr cuts a deal.Hepatitis B Virus X and Regulation of Viral Gene Expression.The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrestFAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy.Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1.Human immunodeficiency virus type 1 Vif induces cell cycle delay via recruitment of the same E3 ubiquitin ligase complex that targets APOBEC3 proteins for degradation.Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction.HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.
P2860
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P2860
Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Human immunodeficiency virus t ...... ion and checkpoint activation.
@en
type
label
Human immunodeficiency virus t ...... ion and checkpoint activation.
@en
prefLabel
Human immunodeficiency virus t ...... ion and checkpoint activation.
@en
P2860
P356
P1433
P1476
Human immunodeficiency virus t ...... ion and checkpoint activation.
@en
P2093
Jason L Dehart
Vicente Planelles
P2860
P304
P356
10.1128/JVI.01628-07
P407
P577
2007-09-12T00:00:00Z