Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution
about
Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidationThe APOBEC3 family of retroelement restriction factorsRegulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzymeComplex structure of Bacillus subtilis RibG: the reduction mechanism during riboflavin biosynthesisLpxI structures reveal how a lipid A precursor is synthesizedStructure of diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase fromAcinetobacter baumanniiEvolution of vitamin B2 biosynthesis: eubacterial RibG and fungal Rib2 deaminases1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal StructureRetroviral restriction by APOBEC proteinsX-Ray Structure and Mutagenesis Studies of the N-Isopropylammelide Isopropylaminohydrolase, AtzCCrystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution.Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complexRole of glutamate 64 in the activation of the prodrug 5-fluorocytosine by yeast cytosine deaminase.A molecular dynamics study of the ligand release path in yeast cytosine deaminaseCatalytic zinc site and mechanism of the metalloenzyme PR-AMP cyclohydrolaseEvaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repairHow similar are enzyme active site geometries derived from quantum mechanical theozymes to crystal structures of enzyme-inhibitor complexes? Implications for enzyme design.Host restriction factors blocking retroviral replicationAntitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminaseA Ser29Leu substitution in the cytosine deaminase Fca1p is responsible for clade-specific flucytosine resistance in Candida dubliniensisStructural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.Emerging implications of nonmammalian cytosine deaminases on cancer therapeutics.Characterization of unexplored amidohydrolase enzyme-pterin deaminase.Antifungal resistance and new strategies to control fungal infections.Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides.NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate.TROSY of side-chain amides in large proteins.Zebrafish AID is capable of deaminating methylated deoxycytidines.Hydrogen-bond detection, configuration assignment and rotamer correction of side-chain amides in large proteins by NMR spectroscopy through protium/deuterium isotope effects.Nonsense and missense mutations in FCY2 and FCY1 genes are responsible for flucytosine resistance and flucytosine-fluconazole cross-resistance in clinical isolates of Candida lusitaniae.Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in Saccharomyces cerevisiae.Mutational analysis of flucytosine resistance in Candida glabrata.Crystal structure of Bacillus subtilis guanine deaminase: the first domain-swapped structure in the cytidine deaminase superfamily.Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes.Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.
P2860
Q24295132-7B87BF3C-ED06-476B-B716-AE6EBC5501FEQ24562606-85D849B9-311D-4EE9-9970-572DA2E4B071Q24672209-B3A0BA95-B12F-402B-A961-7CE0C34AFA3CQ26862780-5BC68518-12AB-4C2B-A445-1CA6BE46BAECQ27646862-3E7E80F2-B7F8-46D3-A9AE-EE432948B9EBQ27652776-837D31E3-C156-4F72-A278-BA0A35E0C9AAQ27674306-01F7B867-5F83-4BFD-B027-06B19F6E10F3Q27678406-B38D05DE-EA04-4090-82AC-0D9D8071A22EQ27683944-9B01C5A4-8097-469E-876A-80795EF8AFB9Q27704805-E411EB3E-2EE5-4009-994D-79DBACE9E120Q28290721-D0DA1F2D-9E19-4642-A0C9-5E5A1D1AE712Q28548310-91702DCF-2435-4BDB-B2CE-AD6048B9B5CDQ30437663-50C449E7-8889-4523-84D3-C9BD55B99F39Q33299999-B14F9519-EB4C-453E-88B3-D4A6281BCEE2Q33402907-45240FC2-1F52-4614-B02F-328CA4AEB9B7Q33650603-135FC902-BC3E-434B-8352-78BFA9BA3B13Q35222236-EF612EF7-FB4B-4982-AB09-5D2E5803BB19Q35738728-1EDA7B7D-DC26-48F7-A8FA-2225CCE01673Q35781262-9F9D196E-AD6F-4A83-9F51-4EFE2D3EE0D4Q36188091-17D56994-C052-464E-98BE-2D203A6A0B4BQ36389685-D2281C6A-2153-4306-9244-4B7401210771Q36393515-64BCD67B-01D2-4255-8056-CE52F59BD48FQ36687748-7541282C-613A-410D-A87A-55B3312AB337Q37251338-8A7D0078-84BC-41CC-9630-331D70C2B270Q37409933-0AAD18C1-7F4D-4ABD-88E6-3B82516427BBQ37629738-80D7F00F-2A00-4D36-BD06-F6AB88DD082EQ38016754-CD7CE55A-30E3-4738-819F-71618CF96C37Q38812103-BC474CA7-227F-4670-9D76-CC6EFE06C140Q39751373-297EE823-9EA4-48F7-8D64-05837D37BCFBQ39891763-2F3F91E7-9A1D-4F52-91F0-BA2C5371F841Q40261713-9D3EB698-213E-41EC-955D-B13D51A2C513Q40865522-0B3C1F04-8994-4322-B836-A7C2D8553BA2Q41074531-AAFA02F0-64D7-4FEE-AF42-480751B46738Q42160276-11B6FFA1-CD21-4F16-910E-E86332924BA2Q42183289-81383485-3B43-4856-98AC-707AB98C9365Q42263592-95686E06-B5F0-40EF-9903-4D156A59727CQ42376066-93542302-6793-4F7E-ADD6-C4CC633B296CQ44924242-79AA8407-8395-42A1-B783-2F703B041FE0Q45147859-AF29ED3C-AEB9-4CB8-957D-B086F727707BQ45242037-C8C941C9-A524-43E8-A9FB-88B1C0F1C009
P2860
Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@ast
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@en
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@nl
type
label
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@ast
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@en
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@nl
prefLabel
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@ast
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@en
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@nl
P2093
P2860
P50
P356
P1476
Crystal structure of yeast cyt ...... enzyme mechanism and evolution
@en
P2093
Chih-Yung Hu
Shwu-Huey Liaw
Yi-Hsin Hsu
P2860
P304
P356
10.1074/JBC.M300874200
P407
P577
2003-05-23T00:00:00Z