Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
about
Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.Expression, purification, assay, and crystal structure of perdeuterated human arginase IStructures of Metal-Substituted Human Histone Deacetylase 8 Provide Mechanistic Inferences on Biological Function,Crystal Structures of Complexes with Cobalt-Reconstituted Human Arginase IFormiminoglutamase from Trypanosoma Cruzi Is An Arginase-Like Manganese MetalloenzymeThe second-shell metal ligands of human arginase affect coordination of the nucleophile and substrate.Replacing Mn(2+) with Co(2+) in human arginase i enhances cytotoxicity toward l-arginine auxotrophic cancer cell lines.Insulin-like growth factor-I induces arginase activity in Leishmania amazonensis amastigote-infected macrophages through a cytokine-independent mechanism.SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis.Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily.Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I.The vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries.Arginase-1 deficiency.Altered dynamics upon oligomerization corresponds to key functional sites.
P2860
Q24532108-C499EC04-BACA-4F15-8AE4-85F550A1A1D5Q24565014-A8C16068-EE5A-40D3-BFDF-314EA0AB48E4Q27662241-E43A2924-B7B5-41F6-968F-B7BCF83E49F5Q27672035-E0359294-7BCA-49B4-AB34-E5B24C8D22BFQ27680665-34D24C09-427D-403C-9A0C-17835EBE39F9Q33739538-2BBCA9C4-F71A-42EE-BC3D-B139C8192957Q33742306-33E3AE5D-7934-445D-9EDB-B291F4B19893Q34247302-A8306205-7759-4C72-8108-D2FEE219F226Q34318551-9ED5D2CA-FD8B-49F6-BDFA-DBE97B047C45Q34346731-B42D917B-77BC-49D7-A9B3-19FAEBE5CE78Q34709337-2744CEA4-B4B3-43E6-BB8C-984CCACF63ECQ36662426-81071F20-BC8F-45D0-88C9-D6BCBB8582EEQ37230853-8F343C06-A41B-4689-92B2-A725309F2D57Q38607205-199DF510-FDD8-42FD-9B13-55888B921BE7Q48312992-F282A3EB-5CAA-4C80-8178-8B57C1573191
P2860
Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural and functional impo ...... anganese cluster of arginase I
@ast
Structural and functional impo ...... anganese cluster of arginase I
@en
Structural and functional impo ...... anganese cluster of arginase I
@nl
type
label
Structural and functional impo ...... anganese cluster of arginase I
@ast
Structural and functional impo ...... anganese cluster of arginase I
@en
Structural and functional impo ...... anganese cluster of arginase I
@nl
prefLabel
Structural and functional impo ...... anganese cluster of arginase I
@ast
Structural and functional impo ...... anganese cluster of arginase I
@en
Structural and functional impo ...... anganese cluster of arginase I
@nl
P2093
P356
P1433
P1476
Structural and functional impo ...... anganese cluster of arginase I
@en
P2093
David E Ash
David W Christianson
Frances A Emig
P304
P356
10.1021/BI030074Y
P407
P577
2003-07-01T00:00:00Z