Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.
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Expression, purification, assay, and crystal structure of perdeuterated human arginase IEvolution of the arginase fold and functional diversityCrystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese clusterSynthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase IProbing the Specificity Determinants of Amino Acid Recognition by Arginase † ‡Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase SoxBInhibition of human arginase I by substrate and product analogues2-Aminoimidazole Amino Acids as Inhibitors of the Binuclear Manganese Metalloenzyme Human Arginase ICrystal Structure of Arginase from Plasmodium falciparum and Implications for l -Arginine Depletion in Malarial Infection,Binding of α,α-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor DesignBinding of the unreactive substrate analogL-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase ICrystal Structures of Complexes with Cobalt-Reconstituted Human Arginase IStructure and Function of Non-Native Metal Clusters in Human Arginase ICrystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infectionsFormiminoglutamase from Trypanosoma Cruzi Is An Arginase-Like Manganese MetalloenzymeCrystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of SchistosomiasisMetal ion-mediated reduction in surface entropy improves diffraction quality of crystals of the IRAK-4 death domainChronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans.Expression, purification and characterization of arginase from Helicobacter pylori in its apo formComputational investigation of the oxidative deboronation of boroglycine, H2N-CH2-B(OH)2, Using H2O and H2O2Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.Role of arginase 1 from myeloid cells in th2-dominated lung inflammation.Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster.Secondary amines containing one aromatic nitro group: preparation, nitrosation, sustained nitric oxide release, and the synergistic effects of released nitric oxide and an arginase inhibitor on vascular smooth muscle cell proliferation.Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I.Arginase and vascular aging.Development of novel arginase inhibitors for therapy of endothelial dysfunctionSchistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity.Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.Arginase: an emerging key player in the mammalian immune system.Small-molecule arginase inhibitors.Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy.Synthesis of a new trifluoromethylketone analogue of l-arginine and contrasting inhibitory activity against human arginase I and histone deacetylase 8.Arginase: an old enzyme with new tricks.Arginase Inhibitors: A Rational Approach Over One Century.Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro.Modulation of contractility by myocyte-derived arginase in normal and hypertrophied feline myocardium.Arginase Structure and Inhibition: Catalytic Site Plasticity Reveals New Modulation Possibilities.
P2860
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P2860
Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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name
Crystal structure of human arg ...... ibition in the immune response
@nl
Crystal structure of human arg ...... bition in the immune response.
@ast
Crystal structure of human arg ...... bition in the immune response.
@en
Crystal structure of human arg ...... bition in the immune response.
@en-gb
type
label
Crystal structure of human arg ...... ibition in the immune response
@nl
Crystal structure of human arg ...... bition in the immune response.
@ast
Crystal structure of human arg ...... bition in the immune response.
@en
Crystal structure of human arg ...... bition in the immune response.
@en-gb
prefLabel
Crystal structure of human arg ...... ibition in the immune response
@nl
Crystal structure of human arg ...... bition in the immune response.
@ast
Crystal structure of human arg ...... bition in the immune response.
@en
Crystal structure of human arg ...... bition in the immune response.
@en-gb
P2093
P2860
P50
P356
P1476
Crystal structure of human arg ...... ibition in the immune response
@en
P2093
Augusto C Ochoa
David W Christianson
Paulo C Rodriguez
P2860
P304
13058-13063
P356
10.1073/PNAS.0504027102
P407
P577
2005-09-02T00:00:00Z