Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions
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Development of Orally Active Thrombin Inhibitors for the Treatment of Thrombotic Disorder DiseasesEngineering Protein Allostery: 1.05 Å Resolution Structure and Enzymatic Properties of a Na+-activated TrypsinHitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes.Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studiesPotent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides.Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.Aromatic rings in chemical and biological recognition: energetics and structures.Prediction of trypsin/molecular fragment binding affinities by free energy decomposition and empirical scores.
P2860
Q26827986-DD0EE5DA-DE45-4E11-B47C-00FB3500D0ADQ27650197-72F01C02-0916-4D6B-8907-247E434C7CC4Q27683710-8E95C4C0-6DBA-4DDF-9287-CF0373EB212FQ35792986-679A58EF-6B00-4F27-9EEB-54691BA9DC7FQ36421786-7FA37CF7-4977-4409-94A3-484A056BCDF2Q37028683-F1BEF885-7FF2-4C7E-BD2D-1759E7C15556Q37871537-577201D6-310B-4D5F-83EA-405FC3DBFC3AQ45739100-F3AB1DC8-0F25-40CE-BA65-87FE042965A1
P2860
Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions
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2007 nî lūn-bûn
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2007 թուականի Մարտին հրատարակուած գիտական յօդուած
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2007 թվականի մարտին հրատարակված գիտական հոդված
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Understanding binding selectiv ...... role of aromatic interactions
@ast
Understanding binding selectiv ...... role of aromatic interactions
@en
Understanding binding selectiv ...... role of aromatic interactions
@nl
type
label
Understanding binding selectiv ...... role of aromatic interactions
@ast
Understanding binding selectiv ...... role of aromatic interactions
@en
Understanding binding selectiv ...... role of aromatic interactions
@nl
prefLabel
Understanding binding selectiv ...... role of aromatic interactions
@ast
Understanding binding selectiv ...... role of aromatic interactions
@en
Understanding binding selectiv ...... role of aromatic interactions
@nl
P2093
P356
P1433
P1476
Understanding binding selectiv ...... role of aromatic interactions
@en
P2093
Andreas Heine
Armida Di Fenza
Ulrich Koert
P2860
P304
P356
10.1002/CMDC.200600185
P577
2007-03-01T00:00:00Z