A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of ChloroquineSynthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depressionTargeting Protein-Protein Interactions in the HIF SystemCyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein InteractionsLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationSynthetic and biological studies of tubulin targeting c2-substituted 7-deazahypoxanthines derived from marine alkaloid rigidinsUnderstanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactionsG-quadruplex recognition by quinacridines: a SAR, NMR, and biological studyDesign and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinasesX-ray structures and thermodynamics of the interaction of PA-IIL from Pseudomonas aeruginosa with disaccharide derivativesCrystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: a new specific binding mode to an a-minor motif enhances in vitro antibacterial activitySynthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesisCarbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform IIDesign and Synthesis of Aryl Ether Inhibitors of theBacillus AnthracisEnoyl-ACP ReductaseTargeting the open-flap conformation of HIV-1 protease with pyrrolidine-based inhibitorsStructure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosisStructure-based optimization of aldose reductase inhibitors originating from virtual screeningFragment-based identification of Hsp90 inhibitorsDesign and biological evaluation of novel, balanced dual PPARalpha/gamma agonistsSynthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives as Phosphodiesterase 7 InhibitorsTruncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided designSilicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biologyOptimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymeraseStructure-Based Design, Synthesis, and Evaluation of 2′-(2-Hydroxyethyl)-2′-deoxyadenosine and the 5′-Diphosphate Derivative as Ribonucleotide Reductase InhibitorsThermodynamic optimisation in drug discovery: a case study using carbonic anhydrase inhibitorsHow to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylaseIdentification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitorFragmenting the S100B-p53 interaction: combined virtual/biophysical screening approaches to identify ligandsInhibition of human DHODH by 4-hydroxycoumarins, fenamic acids, and N-(alkylcarbonyl)anthranilic acids identified by structure-guided fragment selectionFragment-based lead discovery: screening and optimizing fragments for thermolysin inhibitionInhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI)Bidentate Zinc Chelators for α-Carbonic Anhydrases that Produce a Trigonal Bipyramidal Coordination GeometryHigh-resolution crystal structure of a lasso Peptide20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95AUnderstanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acidsProbing Multidrug-Resistance and Protein-Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease InhibitorsThe x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins
P1433
Q22061977-51532F13-3E48-41AC-97EB-BAD9D56A16CDQ24626912-A8A83784-5C23-4455-A78E-A99ED0596CA7Q24630903-AEE80B9E-528D-4F03-9CA3-B22431EE7145Q26753176-E2C1C42E-9D4D-4C23-A120-A1E0C8021B57Q26777298-2C4FEE2D-5EF0-4637-BCD2-8F7A12337FB5Q27021965-32D1B4D9-AF1B-4F9E-B7B9-4BD3F9BA6060Q27336331-6466CFB1-6803-44C7-9D8C-651AA0C3854EQ27643434-E5FF8AAB-7C0C-4C23-81E5-DB03CF4EAA4DQ27644231-C8491F1A-06B6-48B1-A3FD-3D95C11F6DEEQ27644602-1D5CBF9B-6DC5-404B-96AF-EDDF85517425Q27644717-98E0BA93-0B4B-4DA0-A65A-B2B63B8E1CC6Q27646612-EFBB2893-7C0D-49F9-A4BE-4D49EF09DAE2Q27647572-DD08FABA-E68E-4551-80A1-38B8EF2A6EE9Q27649129-25FF2E0F-B8A5-4FD1-956C-7E3D30C2235EQ27649441-7400CB4E-C3F9-489B-BD50-DB8557CE9A36Q27651378-5313B4E5-B43D-4656-9F38-61D0DF999517Q27651746-F08EC669-D3E4-4D94-9F6F-817941BE1801Q27652187-1EA1D6A7-DE19-4F45-8B0B-22024C08E209Q27653366-0C5D8D9D-25DF-4707-976A-F2244E6A0539Q27654218-3C49A3AE-7CBC-4323-B321-1147D59FC2BBQ27654219-1F0AFD8C-45C4-4619-BC92-C3C8BA630210Q27654470-A3D6CEDF-CB68-4637-8212-F5857FF70D4CQ27654567-C79F5544-DCAF-41E5-83BB-6945F8DEAF0AQ27655620-C1726582-9E2F-481A-BCE0-62F3D9F69A02Q27655733-DAA4D281-9041-43F3-9079-959B8DE3377CQ27656967-4649A88F-A2EC-4AC0-9B7A-BB878BAA3517Q27657014-09F2AA4E-E3C8-4549-BBA0-D9CFA270A64CQ27658036-ED42AADF-F506-4B80-9578-09D39BFF4E8EQ27658079-0C7C706C-DDAC-4312-B98D-E6B8769D0A8CQ27658807-F9913C25-68CC-4371-8538-01C1E2F8A15CQ27658965-6C13D1CD-4A13-41B9-B760-9D7540B45D34Q27660047-00BF6D05-1008-4888-9E03-06587FBF3F1DQ27660547-642F8749-91B2-40C6-9435-EB56F612C8D5Q27662071-B03E815F-34D4-4499-834F-0C72E42E5A18Q27663412-59FD41E8-410C-4B77-A4DD-3C31C9CF5FC5Q27663631-86A602FA-8CA4-4B03-A38B-EE19F2DEB236Q27664068-68FA377C-9BBF-4D63-9386-076753842646Q27664256-FC97FB64-E853-4AEB-B983-3FA0FA1B0EFEQ27664394-195DC16C-7916-4D9F-8061-1E0C3B5BDE50Q27664948-9302D934-1604-437C-8DA8-1AEC5498346F
P1433
description
begutachtete wissenschaftliche Fachzeitschrift
@de
peer-reviewed scientific journal
@en
revista científica
@es
rivista scientifica
@it
vědecký časopis
@cs
wetenschappelijk tijdschrift van John Wiley & Sons
@nl
рецензований науковий журнал
@uk
वैज्ञानिक पत्रिका
@hi
name
ChemMedChem
@ast
ChemMedChem
@de
ChemMedChem
@en
ChemMedChem
@es
ChemMedChem
@fr
ChemMedChem
@it
Chemmedchem
@da
Chemmedchem
@fi
Chemmedchem
@nb
Chemmedchem
@nl
type
label
ChemMedChem
@ast
ChemMedChem
@de
ChemMedChem
@en
ChemMedChem
@es
ChemMedChem
@fr
ChemMedChem
@it
Chemmedchem
@da
Chemmedchem
@fi
Chemmedchem
@nb
Chemmedchem
@nl
prefLabel
ChemMedChem
@ast
ChemMedChem
@de
ChemMedChem
@en
ChemMedChem
@es
ChemMedChem
@fr
ChemMedChem
@it
Chemmedchem
@da
Chemmedchem
@fi
Chemmedchem
@nb
Chemmedchem
@nl
P31
P3181
P356
P4616
P646
P1055
P1058
P1156
4400151608
P1159
P123
P1250
P1277
P1476
ChemMedChem
@en
P236
P3181
P356
10.1002/(ISSN)1860-7187
P407
P495
P571
2006-01-01T00:00:00Z
P646
/m/03nn8s5